SDS22_CAEEL
ID SDS22_CAEEL Reviewed; 326 AA.
AC P45969;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 142.
DE RecName: Full=Protein phosphatase 1 regulatory subunit SDS22 homolog;
GN Name=sds-22; ORFNames=T09A5.9;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Regulatory subunit of protein phosphatase 1. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SDS22 family. {ECO:0000305}.
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DR EMBL; Z36753; CAA85336.1; -; Genomic_DNA.
DR PIR; T24722; T24722.
DR RefSeq; NP_495653.1; NM_063252.4.
DR AlphaFoldDB; P45969; -.
DR SMR; P45969; -.
DR BioGRID; 39599; 8.
DR STRING; 6239.T09A5.9; -.
DR iPTMnet; P45969; -.
DR EPD; P45969; -.
DR PaxDb; P45969; -.
DR PeptideAtlas; P45969; -.
DR EnsemblMetazoa; T09A5.9.1; T09A5.9.1; WBGene00011637.
DR GeneID; 174266; -.
DR KEGG; cel:CELE_T09A5.9; -.
DR UCSC; T09A5.9.2; c. elegans.
DR CTD; 174266; -.
DR WormBase; T09A5.9; CE01090; WBGene00011637; sds-22.
DR eggNOG; KOG0531; Eukaryota.
DR GeneTree; ENSGT00940000162473; -.
DR HOGENOM; CLU_044236_0_0_1; -.
DR InParanoid; P45969; -.
DR OMA; YDNLIAH; -.
DR OrthoDB; 968788at2759; -.
DR PhylomeDB; P45969; -.
DR PRO; PR:P45969; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00011637; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046600; P:negative regulation of centriole replication; IGI:WormBase.
DR Gene3D; 3.80.10.10; -; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR003603; U2A'_phosphoprotein32A_C.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00369; LRR_TYP; 5.
DR SMART; SM00446; LRRcap; 1.
DR PROSITE; PS51450; LRR; 10.
PE 3: Inferred from homology;
KW Leucine-rich repeat; Nucleus; Reference proteome; Repeat.
FT CHAIN 1..326
FT /note="Protein phosphatase 1 regulatory subunit SDS22
FT homolog"
FT /id="PRO_0000065456"
FT REPEAT 35..57
FT /note="LRR 1"
FT REPEAT 58..80
FT /note="LRR 2"
FT REPEAT 81..102
FT /note="LRR 3"
FT REPEAT 103..126
FT /note="LRR 4"
FT REPEAT 128..146
FT /note="LRR 5"
FT REPEAT 147..170
FT /note="LRR 6"
FT REPEAT 172..190
FT /note="LRR 7"
FT REPEAT 191..212
FT /note="LRR 8"
FT REPEAT 213..236
FT /note="LRR 9"
FT REPEAT 238..256
FT /note="LRR 10"
FT REPEAT 257..280
FT /note="LRR 11"
FT REPEAT 281..304
FT /note="LRR 12"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 326 AA; 37360 MW; D4C5A5502FF0417B CRC64;
MSNDKSAEVV VLPRENDEES KEPVLKNQFD LSTFDIDSPE IDLTHTRADH IPDLTGFPKI
EELRMRNNLL VSISPTISSL VTLTSLDLYE NQLTEISHLE SLVNLVSLDL SYNRIRQING
LDKLTKLETL YLVSNKIEKI ENLEALTQLK LLELGDNRIK KIENIGHLVN LDELFIGKNK
IRQLEGVETL QKLSVLSLPG NRIVKIENVE QLNNLKELYL SDQGLQDIHG VEPLTNLLLL
DVANNEIKTF SGVERLESLN DFWANDNKVE SFSEIEQLSK LKGLQTVYLE RNPFYFNDTN
QYRRKVMMTL TQVTQIDATT CRKPIE
