ID   SDS23_NEOFI             Reviewed;         538 AA.
AC   A1D3V8;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Protein sds23;
GN   Name=sds23; ORFNames=NFIA_018020;
OS   Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS   / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=331117;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181
RC   / WB 181;
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- FUNCTION: Involved in DNA replication and cell separation.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SDS23 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS027688; EAW23101.1; -; Genomic_DNA.
DR   RefSeq; XP_001264998.1; XM_001264997.1.
DR   AlphaFoldDB; A1D3V8; -.
DR   SMR; A1D3V8; -.
DR   STRING; 36630.CADNFIAP00002066; -.
DR   EnsemblFungi; EAW23101; EAW23101; NFIA_018020.
DR   GeneID; 4591320; -.
DR   KEGG; nfi:NFIA_018020; -.
DR   VEuPathDB; FungiDB:NFIA_018020; -.
DR   eggNOG; KOG1764; Eukaryota.
DR   HOGENOM; CLU_024459_0_0_1; -.
DR   OMA; HRMWVTD; -.
DR   OrthoDB; 841632at2759; -.
DR   Proteomes; UP000006702; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IEA:InterPro.
DR   GO; GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IEA:InterPro.
DR   Gene3D; 3.10.580.10; -; 2.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR016711; Ssd23.
DR   Pfam; PF00571; CBS; 2.
DR   PIRSF; PIRSF018148; UCP018148_CBS_YBR214w; 1.
DR   SMART; SM00116; CBS; 3.
DR   SUPFAM; SSF54631; SSF54631; 2.
DR   PROSITE; PS51371; CBS; 3.
PE   3: Inferred from homology;
KW   CBS domain; Cytoplasm; Nucleus; Reference proteome; Repeat.
FT   CHAIN           1..538
FT                   /note="Protein sds23"
FT                   /id="PRO_0000324955"
FT   DOMAIN          106..171
FT                   /note="CBS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          197..256
FT                   /note="CBS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          274..331
FT                   /note="CBS 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          360..419
FT                   /note="CBS 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   REGION          1..69
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          386..448
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          500..538
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..57
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        386..433
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   538 AA;  57970 MW;  9AEFC06FAE1C2C6F CRC64;
     MADLQNLEAV ADHPNGSAIA SPRSSTDSRS PSTRSQSLRL NHSNHQHRQS FSESLRAAPG
     SPRTRRQPSF TQAAIQSLID NPPAPKDVNP AFAGRDWREI SIGELVRPDD LRFVELDTGI
     EEATNTLIDS DAPVLLIRET PEHKTAVGTF DYSDLNAYLL LAAGLTQPNE ELRESYEELA
     RKARDEHKIP LKDVKELSRS EPLTTLPASA NLMTAVETFG GGVHRVVVVD EHNNGEVVGI
     VSQFRLVKFL WENGRSFPVI DQLYPQYLRD LGIGSREVIS INGDKQLCEA LQIMNSEGIS
     SIAVVDNHSN VVGNISTTDV KLLTRSSSLP LLHNTCIHFI SVILSARGLI EGKDSFPVFY
     VNPSSTLAHT VAKMVATKSH RLWVTDPLSP SSSGPPTPSH SSVQLPLAAS TNSTQSPPVS
     PPATTTNLPA PNYSTPHLPS PPQPFMNAAS LTHPAASVGM PHGVAPSIPA SALPGARLSG
     RLVGVVSLTD ILNLHARASG LSPADPAESR SRRRRSSSSS VSVRKSGDIG RELFSRRD