ID   SDS23_PICGU             Reviewed;         536 AA.
AC   A5DNL9;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 2.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=Protein SDS23;
GN   Name=SDS23; ORFNames=PGUG_04870;
OS   Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS   / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX   NCBI_TaxID=294746;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Involved in DNA replication and cell separation.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SDS23 family. {ECO:0000305}.
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DR   EMBL; CH408160; EDK40772.2; -; Genomic_DNA.
DR   RefSeq; XP_001482915.1; XM_001482865.1.
DR   AlphaFoldDB; A5DNL9; -.
DR   SMR; A5DNL9; -.
DR   STRING; 4929.XP_001482915.1; -.
DR   PRIDE; A5DNL9; -.
DR   EnsemblFungi; EDK40772; EDK40772; PGUG_04870.
DR   GeneID; 5124830; -.
DR   KEGG; pgu:PGUG_04870; -.
DR   VEuPathDB; FungiDB:PGUG_04870; -.
DR   eggNOG; KOG1764; Eukaryota.
DR   HOGENOM; CLU_024459_1_0_1; -.
DR   InParanoid; A5DNL9; -.
DR   OMA; HRMWVTD; -.
DR   OrthoDB; 1471847at2759; -.
DR   Proteomes; UP000001997; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IEA:InterPro.
DR   GO; GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IEA:InterPro.
DR   Gene3D; 3.10.580.10; -; 2.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR016711; Ssd23.
DR   Pfam; PF00571; CBS; 2.
DR   PIRSF; PIRSF018148; UCP018148_CBS_YBR214w; 1.
DR   SMART; SM00116; CBS; 2.
DR   SUPFAM; SSF54631; SSF54631; 2.
DR   PROSITE; PS51371; CBS; 2.
PE   3: Inferred from homology;
KW   CBS domain; Cytoplasm; Nucleus; Reference proteome; Repeat.
FT   CHAIN           1..536
FT                   /note="Protein SDS23"
FT                   /id="PRO_0000324957"
FT   DOMAIN          192..255
FT                   /note="CBS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          267..327
FT                   /note="CBS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   REGION          1..72
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          439..466
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          496..536
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        44..72
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        439..463
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        509..524
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   536 AA;  57224 MW;  8921CE48AF7101A9 CRC64;
     MPNPFSRTPQ SPSQASRKPS VVELLSSPPP LPSPDHDDVH SFSLSRHTSM SSVATGATGD
     RSRGSVSAGT TSGGVDWSDI KLSELTEPQK LISINSGYTV QEAFKTLVTH NLTSVPVSLS
     KTDSSDLENC LSFDYSDLNT YLLLLFGRAR LDALSVDEIN VEGSMSKLEY AQQMVNKAKH
     GGEVPVDFIL RLHPKNPFIK FPEQETLYPA MEALGNGVHR VAITKDSSPH APITGILSQR
     RLIKYMWENA RRFPSLDFLI NSTIQDLNIG SSNPLTIHGD QPLIDALQKM FTERVSSLAV
     IDRSRCLMGN ISIVDVKHVS SSKNQDLLFK SVLNFISYNL SQKGIEAGQD QYPIFHVSNQ
     SSLGRVIAKL VATQSHRLWV VESRQVKHHA SSSGGFGSIS GTRSGSISGA SSAGPVEAAL
     SPQSSSNNSA AAAAAAAASN PSTGSGSVSG SVSGTNSASG TGAGDSGLPG KLIGVVTLTD
     ILGLFAESKY GKKIDPGLAR RQRRRSSTST RSSIDTTQGE IFRKSYTKQE GVFGKE