ID   SDS23_PICST             Reviewed;         530 AA.
AC   A3LQC5;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 2.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Protein SDS23;
GN   Name=SDS23; ORFNames=PICST_88034;
OS   Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS   Y-11545) (Yeast) (Pichia stipitis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX   NCBI_TaxID=322104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX   PubMed=17334359; DOI=10.1038/nbt1290;
RA   Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA   Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA   Passoth V., Richardson P.M.;
RT   "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT   yeast Pichia stipitis.";
RL   Nat. Biotechnol. 25:319-326(2007).
CC   -!- FUNCTION: Involved in DNA replication and cell separation.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SDS23 family. {ECO:0000305}.
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DR   EMBL; CP000496; ABN64657.2; -; Genomic_DNA.
DR   RefSeq; XP_001382686.2; XM_001382649.1.
DR   AlphaFoldDB; A3LQC5; -.
DR   SMR; A3LQC5; -.
DR   STRING; 4924.XP_001382686.2; -.
DR   EnsemblFungi; ABN64657; ABN64657; PICST_88034.
DR   GeneID; 4837336; -.
DR   KEGG; pic:PICST_88034; -.
DR   eggNOG; KOG1764; Eukaryota.
DR   HOGENOM; CLU_024459_1_0_1; -.
DR   InParanoid; A3LQC5; -.
DR   OMA; HRMWVTD; -.
DR   OrthoDB; 1471847at2759; -.
DR   Proteomes; UP000002258; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IEA:InterPro.
DR   GO; GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IEA:InterPro.
DR   Gene3D; 3.10.580.10; -; 2.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR016711; Ssd23.
DR   Pfam; PF00571; CBS; 1.
DR   PIRSF; PIRSF018148; UCP018148_CBS_YBR214w; 1.
DR   SMART; SM00116; CBS; 3.
DR   SUPFAM; SSF54631; SSF54631; 2.
DR   PROSITE; PS51371; CBS; 2.
PE   3: Inferred from homology;
KW   CBS domain; Cytoplasm; Nucleus; Reference proteome; Repeat.
FT   CHAIN           1..530
FT                   /note="Protein SDS23"
FT                   /id="PRO_0000324958"
FT   DOMAIN          213..274
FT                   /note="CBS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          289..347
FT                   /note="CBS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   REGION          1..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          65..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          467..509
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..23
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   530 AA;  58600 MW;  19CA0E2799401F91 CRC64;
     MSNPPFQRQQ PSSPLTTPNH HPSNHQHHAS RKPSIVELLS SPPPLPNNTI DDEIHQFSLS
     RNTSISSRTS SFSQQQHGAP HHGSNSHHLS VSGMDWSEIP LSELTESNKL IYINSSYSVQ
     KAFETLVSNN LTSVPVSISS SNENDLSSCL TFDYSDLNTY LLLIMNKINL SELSVSEIGN
     EHDSTAKKHE IITQTINKAK RGEEVPIEFI IKLHPKNPFI KFTENDTLFK VMETLGNGVH
     RVAITNLEST KITGILSQRR LIKYMWENAR RFPSLDFYLN STLQDLKIGS STPIFIYEDQ
     LLIEALYKMF NERVSSLAVI DRTKSLIGNI SIVDVKNVSS SKNSHLLFKS VLTFISYNLS
     QKGIEEGQDQ YPIFHVNKQS SLGRVIAKLV ATQSHRLWIV ESNTRTHQNS ISSPVTIEAT
     LNVSANPSSA SSSNANTPEG NFGLPGKLIG VVTLTDILGL FATSKGTKTD PQFARNQRRR
     SSTSTTRSSI DSAISVGDGS ARTTNANADS EIFRKSYTAA AKNESAISKD