ID   SDS23_VANPO             Reviewed;         525 AA.
AC   A7TL18;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Protein SDS23;
GN   Name=SDS23; ORFNames=Kpol_530p44;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: Involved in DNA replication and cell separation.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SDS23 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS480411; EDO17074.1; -; Genomic_DNA.
DR   RefSeq; XP_001644932.1; XM_001644882.1.
DR   AlphaFoldDB; A7TL18; -.
DR   SMR; A7TL18; -.
DR   STRING; 436907.A7TL18; -.
DR   EnsemblFungi; EDO17074; EDO17074; Kpol_530p44.
DR   GeneID; 5545266; -.
DR   KEGG; vpo:Kpol_530p44; -.
DR   eggNOG; KOG1764; Eukaryota.
DR   HOGENOM; CLU_024459_1_1_1; -.
DR   InParanoid; A7TL18; -.
DR   OMA; MYHERIS; -.
DR   OrthoDB; 1471847at2759; -.
DR   PhylomeDB; A7TL18; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IEA:InterPro.
DR   GO; GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IEA:InterPro.
DR   Gene3D; 3.10.580.10; -; 2.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR016711; Ssd23.
DR   Pfam; PF00571; CBS; 2.
DR   PIRSF; PIRSF018148; UCP018148_CBS_YBR214w; 1.
DR   SMART; SM00116; CBS; 4.
DR   SUPFAM; SSF54631; SSF54631; 2.
DR   PROSITE; PS51371; CBS; 4.
PE   3: Inferred from homology;
KW   CBS domain; Cytoplasm; Nucleus; Reference proteome; Repeat.
FT   CHAIN           1..525
FT                   /note="Protein SDS23"
FT                   /id="PRO_0000324961"
FT   DOMAIN          154..215
FT                   /note="CBS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          238..296
FT                   /note="CBS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          323..382
FT                   /note="CBS 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          439..508
FT                   /note="CBS 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   REGION          1..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          438..475
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        441..475
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   525 AA;  58060 MW;  28FF428575FE1B90 CRC64;
     MSTNISNKNS MSTSGSNNNT NNNNNSGCSS SNSSQRHNSI VELLSTPPQL PHQHHFNKSR
     QNSNLNESMS DSGESGLRRV DSYSSNDSIS ILSINSAHNH TDVGDVIINN ELTASTTAST
     VGSGNSNQLT QTTSQCISST HSQKWQHIQL TQLIEQNKLI TVQGSISIEE AFNTLMKYHL
     TSLPVESYPG DMNCFTFDYN DLNSYLLLVL NKITVNNREI TQDCQNGKPV PVGEIIKLTP
     KNPFYKLPET ENLSTVLGIL GSGVHRVAIT NTEMTKIKGI LSQRRLIKYL WDNARSFPSL
     EPLFNSSLQE LQIGVLNTHS KPTSKQSRVI SIQGEEPLIN ALYKIHEERI SSIAVVDHQN
     NLIGNISVTD VKYVTRTSQY PLLHNTCRHF ISVILNTRGL EMGKDSFPIF HVYPTSSLAR
     TLAKLVATKS HRLWIVQPPE PSDINTGNTS NPASSHSPMM TAVDHSPSQT PNVSPTNLFE
     KEYRTGKLIG VISLTDILSV LARKQTDNKQ VDPLSARRQR GSVSM