ID   SDS23_YEAS7             Reviewed;         527 AA.
AC   A6ZUC0;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 43.
DE   RecName: Full=Protein SDS23;
GN   Name=SDS23; ORFNames=SCY_2003;
OS   Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=307796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJM789;
RX   PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA   Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA   Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA   Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA   Steinmetz L.M.;
RT   "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT   strain YJM789.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC   -!- FUNCTION: Involved in DNA replication and cell separation during
CC       budding. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SDS23 family. {ECO:0000305}.
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DR   EMBL; AAFW02000099; EDN62058.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6ZUC0; -.
DR   SMR; A6ZUC0; -.
DR   EnsemblFungi; EDN62058; EDN62058; SCY_2003.
DR   HOGENOM; CLU_024459_1_1_1; -.
DR   Proteomes; UP000007060; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IEA:InterPro.
DR   GO; GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IEA:InterPro.
DR   Gene3D; 3.10.580.10; -; 2.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR016711; Ssd23.
DR   Pfam; PF00571; CBS; 2.
DR   PIRSF; PIRSF018148; UCP018148_CBS_YBR214w; 1.
DR   SMART; SM00116; CBS; 2.
DR   SUPFAM; SSF54631; SSF54631; 2.
DR   PROSITE; PS51371; CBS; 3.
PE   3: Inferred from homology;
KW   CBS domain; Cytoplasm; Nucleus; Phosphoprotein; Repeat.
FT   CHAIN           1..527
FT                   /note="Protein SDS23"
FT                   /id="PRO_0000324963"
FT   DOMAIN          101..162
FT                   /note="CBS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          185..243
FT                   /note="CBS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          272..330
FT                   /note="CBS 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          335..391
FT                   /note="CBS 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   REGION          1..75
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          385..481
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..35
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        49..75
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        385..457
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        458..474
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         9
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P53172"
FT   MOD_RES         42
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P53172"
FT   MOD_RES         46
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P53172"
FT   MOD_RES         430
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P53172"
SQ   SEQUENCE   527 AA;  58098 MW;  8AB2A9E337887F19 CRC64;
     MPQNTRHTSI VEMLSTPPQL PNSTDLNSLS EQTDKNTEAN KSDTESLHKS ISKSSSSSSL
     STLDNTEYSN NNGNSLSTLN SQNLLSVHRQ EWQHTPLSNL VEQNKLIFIR GSISVEEAFN
     TLVKHQLTSL PVENFPGDMN CLTFDYNDLN AYLLLVLNRI KVSNDKITSD CQNGKSVPVG
     EIVKLTPKNP FYKLPETENL STVIGILGSG VHRVAITNVE MTQIKGILSQ RRLIKYLWEN
     ARSFPNLKPL LDSSLEELNI GVLNAARDKP TFKQSRVISI QGDEHLIMAL HKMYVERISS
     IAVVDPQGNL IGNISVTDVK HVTRTSQYPL LHNTCRHFVS VILNLRGLET GKDSFPIFHV
     YPTSSLARTF AKLVATKSHR LWIVQPNDNQ PTASSEKSSS PSPSTPPVTT LPSLASSYHS
     NTQSSRMANS PVLKSSDTSN NKINVNINLS GPSPSQPQSP STAMPPPQSP SNCPASPTPA
     HFEKEYRTGK LIGVVSLTDI LSVLARKQTH HKEIDPQMAR KQRGHIG