SDU1_SCHPO
ID SDU1_SCHPO Reviewed; 201 AA.
AC Q8X1T0; Q9P7Y6;
DT 31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=DeSI-like protein sdu1;
DE EC=3.4.-.-;
DE AltName: Full=Meiotically up-regulated gene 67 protein;
GN Name=sdu1; Synonyms=hag1, mug67; ORFNames=SPAPYUG7.06;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11041002;
RA Shpakovski G.V., Baranova G.M.;
RT "Chromosomal localization of the rpb9+ and tfa1+ genes encoding components
RT of the mRNA synthesis machinery of Schizosaccharomyces pombe.";
RL Bioorg. Khim. 26:623-630(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [3]
RP FUNCTION IN MEIOSIS.
RX PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P.,
RA Smith G.R., Moreno S.;
RT "A large-scale screen in S. pombe identifies seven novel genes required for
RT critical meiotic events.";
RL Curr. Biol. 15:2056-2062(2005).
RN [4]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the DeSI family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF237420; AAL55664.1; -; Genomic_DNA.
DR EMBL; CU329670; CAB66315.2; -; Genomic_DNA.
DR PIR; T50306; T50306.
DR RefSeq; NP_594707.2; NM_001020134.2.
DR AlphaFoldDB; Q8X1T0; -.
DR SMR; Q8X1T0; -.
DR BioGRID; 279374; 20.
DR STRING; 4896.SPAPYUG7.06.1; -.
DR iPTMnet; Q8X1T0; -.
DR MaxQB; Q8X1T0; -.
DR PaxDb; Q8X1T0; -.
DR PRIDE; Q8X1T0; -.
DR EnsemblFungi; SPAPYUG7.06.1; SPAPYUG7.06.1:pep; SPAPYUG7.06.
DR GeneID; 2542933; -.
DR KEGG; spo:SPAPYUG7.06; -.
DR PomBase; SPAPYUG7.06; sdu1.
DR VEuPathDB; FungiDB:SPAPYUG7.06; -.
DR eggNOG; KOG0324; Eukaryota.
DR HOGENOM; CLU_069001_5_2_1; -.
DR InParanoid; Q8X1T0; -.
DR OMA; PFRTSIN; -.
DR PhylomeDB; Q8X1T0; -.
DR PRO; PR:Q8X1T0; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0101005; F:deubiquitinase activity; EXP:PomBase.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0016926; P:protein desumoylation; ISS:PomBase.
DR GO; GO:0016579; P:protein deubiquitination; EXP:PomBase.
DR GO; GO:0070646; P:protein modification by small protein removal; IBA:GO_Central.
DR Gene3D; 3.90.1720.30; -; 1.
DR InterPro; IPR008580; PPPDE_dom.
DR InterPro; IPR042266; PPPDE_sf.
DR PANTHER; PTHR12378; PTHR12378; 1.
DR Pfam; PF05903; Peptidase_C97; 1.
DR SMART; SM01179; DUF862; 1.
DR PROSITE; PS51858; PPPDE; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Hydrolase; Meiosis; Protease; Reference proteome.
FT CHAIN 1..201
FT /note="DeSI-like protein sdu1"
FT /id="PRO_0000221634"
FT DOMAIN 1..143
FT /note="PPPDE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01205"
FT REGION 146..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..181
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 29
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01205"
FT ACT_SITE 105
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01205"
SQ SEQUENCE 201 AA; 21952 MW; 62E5C740AD790361 CRC64;
MKVYINVYDL MPDSPVNKLA WTLGLGIYHT GLVLEGKEYA FGAHEIPGST GVFATMPRPP
LEGCRWRCSI ALPNCTLPKP DVDRILIRLS QEFTGLSYSL LERNCNHFTN AAAIELTGSP
IPSFLNRISR IGLAFPTITN ALLQHGQKNT SDVDDSSDSS SDVDEETLIV SKSKKAHKDI
PKFSAPPPSA DLNNLITDSL P
