SEAS1_HUMAN
ID SEAS1_HUMAN Reviewed; 156 AA.
AC Q5TG53;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 2.
DT 25-MAY-2022, entry version 76.
DE RecName: Full=Putative uncharacterized protein SERTAD4-AS1;
DE AltName: Full=SERTAD4 antisense RNA 1;
DE AltName: Full=SERTAD4 antisense gene protein 1;
GN Name=SERTAD4-AS1; Synonyms=C1orf133;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16710414; DOI=10.1038/nature04727;
RA Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A.,
RA Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C.,
RA Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.,
RA Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C.,
RA Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W.,
RA Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J.,
RA Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J.,
RA Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y.,
RA Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J.,
RA Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S.,
RA Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K.,
RA Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R.,
RA Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M.,
RA Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S.,
RA Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J.,
RA Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W.,
RA McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N.,
RA Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V.,
RA Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J.,
RA Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E.,
RA Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S.,
RA Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M.,
RA White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H.,
RA Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E.,
RA Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G.,
RA Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.;
RT "The DNA sequence and biological annotation of human chromosome 1.";
RL Nature 441:315-321(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC TISSUE=Hypothalamus, and Placenta;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q5TG53-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q5TG53-2; Sequence=VSP_035119;
CC -!- CAUTION: Product of a dubious CDS prediction. {ECO:0000305}.
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DR EMBL; AL035414; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC066352; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; BC094794; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; Q5TG53; -.
DR IntAct; Q5TG53; 1.
DR iPTMnet; Q5TG53; -.
DR PhosphoSitePlus; Q5TG53; -.
DR BioMuta; HGNC:32019; -.
DR PRIDE; Q5TG53; -.
DR GeneCards; SERTAD4-AS1; -.
DR HGNC; HGNC:32019; SERTAD4-AS1.
DR neXtProt; NX_Q5TG53; -.
DR TreeFam; TF353672; -.
DR ChiTaRS; SERTAD4-AS1; human.
DR Pharos; Q5TG53; Tdark.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q5TG53; protein.
PE 5: Uncertain;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..156
FT /note="Putative uncharacterized protein SERTAD4-AS1"
FT /id="PRO_0000346443"
FT REGION 1..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 129..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 46..82
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 78..156
FT /note="GELRTEEPPPPAARLCCLGGGCGGGGGGGQKVSATASIPFSCKRALLTSTIP
FT LSPPAKRRGIRTWGHPSYLTPSPTMRD -> VILRL (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:15489334"
FT /id="VSP_035119"
FT VARIANT 91
FT /note="R -> Q (in dbSNP:rs624270)"
FT /id="VAR_046125"
SQ SEQUENCE 156 AA; 16212 MW; 073B819811FC0B03 CRC64;
MSARPSLPPL PAKPAGSPRL RERPAPVGPG GEDAYSLLLR PQLGTRKVAR AEEAGGEEGK
REAEAWTRRA AASARRGGEL RTEEPPPPAA RLCCLGGGCG GGGGGGQKVS ATASIPFSCK
RALLTSTIPL SPPAKRRGIR TWGHPSYLTP SPTMRD
