ID   SEBOX_RAT               Reviewed;         188 AA.
AC   Q9ERS8;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Homeobox protein SEBOX;
DE   AltName: Full=Homeobox OG-9;
DE   AltName: Full=Skin-, embryo-, brain- and oocyte-specific homeobox;
GN   Name=Sebox; Synonyms=Og9x;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Sprague-Dawley;
RX   PubMed=10922053; DOI=10.1073/pnas.97.16.8904;
RA   Cinquanta M., Rovescalli A.C., Kozak C.A., Nirenberg M.;
RT   "Mouse Sebox homeobox gene expression in skin, brain, oocytes, and two-cell
RT   embryos.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:8904-8909(2000).
CC   -!- FUNCTION: Probable transcription factor involved in the control of
CC       specification of mesoderm and endoderm. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
CC   -!- SIMILARITY: Belongs to the paired homeobox family. {ECO:0000305}.
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DR   EMBL; AF284338; AAG14459.1; -; Genomic_DNA.
DR   RefSeq; NP_076441.1; NM_023951.1.
DR   AlphaFoldDB; Q9ERS8; -.
DR   SMR; Q9ERS8; -.
DR   STRING; 10116.ENSRNOP00000013296; -.
DR   PaxDb; Q9ERS8; -.
DR   PRIDE; Q9ERS8; -.
DR   GeneID; 58922; -.
DR   KEGG; rno:58922; -.
DR   CTD; 645832; -.
DR   RGD; 62077; Sebox.
DR   eggNOG; KOG0490; Eukaryota.
DR   InParanoid; Q9ERS8; -.
DR   OrthoDB; 1270742at2759; -.
DR   PhylomeDB; Q9ERS8; -.
DR   PRO; PR:Q9ERS8; -.
DR   Proteomes; UP000002494; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009792; P:embryo development ending in birth or egg hatching; ISO:RGD.
DR   GO; GO:0048477; P:oogenesis; ISO:RGD.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR042223; SEBOX.
DR   PANTHER; PTHR47777; PTHR47777; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   3: Inferred from homology;
KW   Developmental protein; Differentiation; DNA-binding; Homeobox; Nucleus;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..188
FT                   /note="Homeobox protein SEBOX"
FT                   /id="PRO_0000311338"
FT   DNA_BIND        18..77
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          80..125
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        94..125
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   188 AA;  20196 MW;  C7F649EBCC35F9B0 CRC64;
     MASPVEASPG CASGLGPHRR KRTTFSVGQL LELERVFAAR PYPDISTREH LAQITHLPEA
     KIQVWFQNRR AKRIKDRKPG ALNARLELPP NCSLPDTPQL SWDPGTPSHP LHSTSSAQQT
     SACPPQTSCL APILGPGQSW SGAKAAAPWG TSEVSGVHSL EQIVPQTSLG NLSDLIYTSA
     IVTNVDHS