ID   BFR2_ASPFU              Reviewed;         565 AA.
AC   Q4WMI1;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Protein bfr2;
GN   Name=bfr2; ORFNames=AFUA_6G09820;
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=330879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA   Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA   Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA   Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA   Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA   Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA   Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA   O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA   Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA   Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA   Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA   Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA   Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA   Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA   Barrell B.G., Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AATF family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAHF01000006; EAL88833.1; -; Genomic_DNA.
DR   RefSeq; XP_750871.1; XM_745778.1.
DR   AlphaFoldDB; Q4WMI1; -.
DR   SMR; Q4WMI1; -.
DR   STRING; 746128.CADAFUBP00007391; -.
DR   EnsemblFungi; EAL88833; EAL88833; AFUA_6G09820.
DR   GeneID; 3508176; -.
DR   KEGG; afm:AFUA_6G09820; -.
DR   VEuPathDB; FungiDB:Afu6g09820; -.
DR   eggNOG; KOG2773; Eukaryota.
DR   HOGENOM; CLU_018299_2_2_1; -.
DR   InParanoid; Q4WMI1; -.
DR   OMA; LINFMAP; -.
DR   OrthoDB; 794860at2759; -.
DR   Proteomes; UP000002530; Chromosome 6.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   InterPro; IPR025160; AATF.
DR   InterPro; IPR039223; AATF/Bfr2.
DR   InterPro; IPR012617; AATF_C.
DR   PANTHER; PTHR15565; PTHR15565; 2.
DR   Pfam; PF13339; AATF-Che1; 1.
DR   Pfam; PF08164; TRAUB; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..565
FT                   /note="Protein bfr2"
FT                   /id="PRO_0000056622"
FT   REGION          1..225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          404..430
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          537..565
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..26
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        78..95
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        96..122
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        123..154
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        155..205
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        206..225
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        410..427
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   565 AA;  62611 MW;  0521264B00A5E828 CRC64;
     MAPKTLAERL AELEDPTPKD FDPEDLERAG PDSDDEGNEA ADPNAGREHY QAVGKARLRR
     QDPINLGKQY AGSKISREAL EAESDDDPFR PRSSDEEEDS EDEEEEDSEL GSDEDEDASE
     ESEEERPQRS RTSAKDSKRQ RKESQVSSDE KDGEGMDTDG SEETEGSEDD SEDGFDEDDM
     SGEFSSDDDQ EGDEDGDDDE DEDEETDNRK VRFQETSKSD DREELRRLMS SDQKTIAATI
     SQAAKADAAK GRAVKQQRAT FDALLNARIK LQKGLTAINR LSVTTKGSDE TPSIDGEAIK
     SAESAALALW STLEDLRLAL ADAQTQDESK KRKRPSAVSV ATSTDSLWKR MTDLESDAVP
     HRRTVLDKWS LKVRGSTAAL PNARGKLLGA SASSQQTISA VIDAQVASET GDRAAKRRRH
     SSDEGPEPVY DDTVFYQSLL RDLVEQRMSS SDAITNGIDT LHLQLPSRQG IHPITGMRKD
     KVKRDVDTRA SKGRKMRFDV HEKLQNFMAP EDRGTWTITA REEFFASLLG KTASGLLREG
     DDEDASAAEE SDEDREEVGL RLFRS