ID   BFR2_CRYNB              Reviewed;         463 AA.
AC   P0CL91; Q55NE3; Q5KBS9;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Protein BFR2;
GN   Name=BFR2; OrderedLocusNames=CNBH1440;
OS   Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
OS   (Filobasidiella neoformans).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus neoformans species complex.
OX   NCBI_TaxID=283643;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B-3501A;
RX   PubMed=15653466; DOI=10.1126/science.1103773;
RA   Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA   Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA   Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA   Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA   Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J.,
RA   Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA   Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA   Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA   Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA   Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT   "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT   neoformans.";
RL   Science 307:1321-1324(2005).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AATF family. {ECO:0000305}.
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DR   EMBL; AAEY01000042; EAL19042.1; -; Genomic_DNA.
DR   RefSeq; XP_773689.1; XM_768596.1.
DR   AlphaFoldDB; P0CL91; -.
DR   EnsemblFungi; AAW45370; AAW45370; CNI01530.
DR   EnsemblFungi; EAL19042; EAL19042; CNBH1440.
DR   GeneID; 4937664; -.
DR   KEGG; cnb:CNBH1440; -.
DR   VEuPathDB; FungiDB:CNBH1440; -.
DR   HOGENOM; CLU_018299_2_1_1; -.
DR   Proteomes; UP000001435; Chromosome 8.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR025160; AATF.
DR   InterPro; IPR039223; AATF/Bfr2.
DR   InterPro; IPR012617; AATF_C.
DR   PANTHER; PTHR15565; PTHR15565; 1.
DR   Pfam; PF13339; AATF-Che1; 1.
DR   Pfam; PF08164; TRAUB; 1.
PE   3: Inferred from homology;
KW   Nucleus.
FT   CHAIN           1..463
FT                   /note="Protein BFR2"
FT                   /id="PRO_0000409996"
FT   REGION          14..174
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        14..30
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        31..51
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        83..144
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   463 AA;  50648 MW;  B1F95EAF94B18D40 CRC64;
     MSGLSLAQQL KQLHSNNVSV PDPESAYSNL DSHDIQRKGD EGREHYVDVG PSRLRMELGG
     TGGGTLTGPK YEGVKTGRMK IFDDDDDDDD DREGNGSEEG SDGEGDEDED GDEDDEDEED
     EDEDEEESDE DEQGEDEDED EEEQPQPRAN GSKQALDPVA SLRNSRLKDV EKGQAIRKQK
     ALFESLITLR ITFQKALTAS NTVPPTLPED PENELAYKKA SILKSLGELN ERLFTLRESI
     SLPGELGEDV SLGKRKRAEG DDAQGQAYWI KAAKESLGIA DRSHPQLLPI LNKWSSKIQA
     ASLQLGSKQA GGSKFLQQMK NGAGGVVEAI ESGINSKREA EKTLMESEET GYRALLREVI
     ESRSGSGPAA DLTHLRREKK KKREAERGGS KGRKLRYTVH EKAQNFVVPI PLSHGWHEEQ
     VDELFSSLFG GVGMKGATAE KTVGLDVGTA DEGLAELGGL RVF