ID   BFR2_GIBZE              Reviewed;         538 AA.
AC   Q4I327; A0A098DE39; A0A0E0RZN7; V6RKI1;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Protein BFR2;
GN   Name=BFR2; ORFNames=FGRRES_08381, FGSG_08381;
OS   Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084
OS   / PH-1) (Wheat head blight fungus) (Fusarium graminearum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX   NCBI_TaxID=229533;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX   PubMed=17823352; DOI=10.1126/science.1143708;
RA   Cuomo C.A., Gueldener U., Xu J.-R., Trail F., Turgeon B.G., Di Pietro A.,
RA   Walton J.D., Ma L.-J., Baker S.E., Rep M., Adam G., Antoniw J., Baldwin T.,
RA   Calvo S.E., Chang Y.-L., DeCaprio D., Gale L.R., Gnerre S., Goswami R.S.,
RA   Hammond-Kosack K., Harris L.J., Hilburn K., Kennell J.C., Kroken S.,
RA   Magnuson J.K., Mannhaupt G., Mauceli E.W., Mewes H.-W., Mitterbauer R.,
RA   Muehlbauer G., Muensterkoetter M., Nelson D., O'Donnell K., Ouellet T.,
RA   Qi W., Quesneville H., Roncero M.I.G., Seong K.-Y., Tetko I.V., Urban M.,
RA   Waalwijk C., Ward T.J., Yao J., Birren B.W., Kistler H.C.;
RT   "The Fusarium graminearum genome reveals a link between localized
RT   polymorphism and pathogen specialization.";
RL   Science 317:1400-1402(2007).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX   PubMed=20237561; DOI=10.1038/nature08850;
RA   Ma L.-J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.-J.,
RA   Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA   Houterman P.M., Kang S., Shim W.-B., Woloshuk C., Xie X., Xu J.-R.,
RA   Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA   Butchko R.A.E., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.J.,
RA   Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA   Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA   Kumar L., Lee Y.-H., Li L., Manners J.M., Miranda-Saavedra D.,
RA   Mukherjee M., Park G., Park J., Park S.-Y., Proctor R.H., Regev A.,
RA   Ruiz-Roldan M.C., Sain D., Sakthikumar S., Sykes S., Schwartz D.C.,
RA   Turgeon B.G., Wapinski I., Yoder O., Young S., Zeng Q., Zhou S.,
RA   Galagan J., Cuomo C.A., Kistler H.C., Rep M.;
RT   "Comparative genomics reveals mobile pathogenicity chromosomes in
RT   Fusarium.";
RL   Nature 464:367-373(2010).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX   PubMed=26198851; DOI=10.1186/s12864-015-1756-1;
RA   King R., Urban M., Hammond-Kosack M.C.U., Hassani-Pak K.,
RA   Hammond-Kosack K.E.;
RT   "The completed genome sequence of the pathogenic ascomycete fungus Fusarium
RT   graminearum.";
RL   BMC Genomics 16:544-544(2015).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AATF family. {ECO:0000305}.
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DR   EMBL; DS231667; ESU14971.1; -; Genomic_DNA.
DR   EMBL; HG970333; CEF76712.1; -; Genomic_DNA.
DR   RefSeq; XP_011320396.1; XM_011322094.1.
DR   AlphaFoldDB; Q4I327; -.
DR   SMR; Q4I327; -.
DR   STRING; 5518.FGSG_08381P0; -.
DR   PRIDE; Q4I327; -.
DR   EnsemblFungi; ESU14971; ESU14971; FGSG_08381.
DR   GeneID; 23555389; -.
DR   KEGG; fgr:FGSG_08381; -.
DR   VEuPathDB; FungiDB:FGRAMPH1_01G09819; -.
DR   eggNOG; KOG2773; Eukaryota.
DR   HOGENOM; CLU_018299_2_0_1; -.
DR   InParanoid; Q4I327; -.
DR   Proteomes; UP000070720; Chromosome 2.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR025160; AATF.
DR   InterPro; IPR039223; AATF/Bfr2.
DR   InterPro; IPR012617; AATF_C.
DR   PANTHER; PTHR15565; PTHR15565; 1.
DR   Pfam; PF13339; AATF-Che1; 1.
DR   Pfam; PF08164; TRAUB; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Reference proteome.
FT   CHAIN           1..538
FT                   /note="Protein BFR2"
FT                   /id="PRO_0000056628"
FT   REGION          1..239
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          290..363
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..56
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        82..107
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..139
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        168..220
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   538 AA;  59594 MW;  8854403B1B2171D2 CRC64;
     MVKAKGRAKE FQDPDEPITK DYDPEADVDV SEHGSGSEDS EDENAGTEHY VSVGKSKLRK
     SEGLSLGPQY RGSRVSRDAL EEESASEEDD EEGSGDEEFD DPETADLERD AAEANDSEIS
     SDNALGESDE ERFKDYTFRA SSKPNKPLSK RAKAADYMSS SDNEGAELGG SDSEDEEMDD
     GLDALVDGEG DSDDESDEND DEEGSGDDEE DDEDDSESDE EDSKAKAQNA KPMMAALSTQ
     PDVDKGLAIR QQRKAYDGLL NMRIRLQKAL IAANTFEALD SNPEPESEPY EAAEEAAIKL
     LNTISSLKDN FGPSHAGEKR KRELDVSMTT SQIWEQMQAE EERAIKSRED RLEKWSRKVQ
     SVNVTGPKGL EGRNKTLISA LRDQLINPDN RLAKRSRVPR SCAPAQAAKG VSEDNNIYDD
     ADFYQVLLKE LVDQRTVEGS SGAGAGDAVP TVVLTASKDV KNRKNVDRKA SKGRKMRFTV
     HEKMQNFMAP EDRRAWEQGA IDRFFGTLFG RKMQLNEDES DDDMDVDVEE AGLRLFRN