ID   BFR2_KLULA              Reviewed;         526 AA.
AC   Q6CTS8;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Protein BFR2;
GN   Name=BFR2; OrderedLocusNames=KLLA0C10362g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AATF family. {ECO:0000305}.
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DR   EMBL; CR382123; CAH01512.1; -; Genomic_DNA.
DR   RefSeq; XP_452661.1; XM_452661.1.
DR   AlphaFoldDB; Q6CTS8; -.
DR   SMR; Q6CTS8; -.
DR   STRING; 28985.XP_452661.1; -.
DR   EnsemblFungi; CAH01512; CAH01512; KLLA0_C10362g.
DR   GeneID; 2892016; -.
DR   KEGG; kla:KLLA0_C10362g; -.
DR   eggNOG; KOG2773; Eukaryota.
DR   HOGENOM; CLU_018299_2_2_1; -.
DR   InParanoid; Q6CTS8; -.
DR   OMA; LINFMAP; -.
DR   Proteomes; UP000000598; Chromosome C.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0032040; C:small-subunit processome; IEA:EnsemblFungi.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   InterPro; IPR025160; AATF.
DR   InterPro; IPR039223; AATF/Bfr2.
DR   InterPro; IPR012617; AATF_C.
DR   PANTHER; PTHR15565; PTHR15565; 1.
DR   Pfam; PF13339; AATF-Che1; 1.
DR   Pfam; PF08164; TRAUB; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..526
FT                   /note="Protein BFR2"
FT                   /id="PRO_0000056629"
FT   REGION          16..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          82..149
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..32
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        93..110
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        112..135
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   526 AA;  59455 MW;  9D45FE7614B3DE7D CRC64;
     MGKKSLAEQI ADIANKPQVE DFDIENDEGV FQHGGSDSDV SSGDESEEEL KKQHYVAVGK
     SKLRNVVDQG LAVKDKKYVG SKGSRAELFN DEEMDAPEQG ESESEAESGS EESDAVSFRS
     DSEDVSESEA TSESEIEKDR EEDEETAMKK EKLAKIVQTQ TKQVINNLAH SAQRDASKGY
     AILQQNKFFD KILDSRIKLQ KALSASNQLP LSQQSWDELL DENNSKLLTS TFKVLEKVLT
     QCVTVRHKFQ IGDHINQSEN PSDFDNSKKR SFKELVHETV TLDSDLKSYR SAVLNKWSAK
     VSASSGKSLL QASKFKAINQ SADVQVDNQL ADMPRLLKRT KLNRSNTKPL LFDEDLQKGL
     LKELQLEENV EGDIEEENNL DIPKNYDPRR KDNNALDFTQ NPYIYDDEDF YRVLLNDLVE
     KKISNSQQSN GVTLAITSRS ENKLKKNIDT KASKGRKLNY SIQEPIANYE ASVNTGYKWS
     DEQIDEFFAG LLGQKINFNE DDELEADTMH NEEDEEIKND DIQIFG