ID   BFR2_NEUCR              Reviewed;         636 AA.
AC   Q7S6P8;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Protein bfr2;
GN   Name=bfr2; ORFNames=B15B10.001, NCU04787;
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12655011; DOI=10.1093/nar/gkg293;
RA   Mannhaupt G., Montrone C., Haase D., Mewes H.-W., Aign V., Hoheisel J.D.,
RA   Fartmann B., Nyakatura G., Kempken F., Maier J., Schulte U.;
RT   "What's in the genome of a filamentous fungus? Analysis of the Neurospora
RT   genome sequence.";
RL   Nucleic Acids Res. 31:1944-1954(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA   Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA   Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA   Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA   Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA   Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA   Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AATF family. {ECO:0000305}.
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DR   EMBL; BX897677; CAE85565.1; -; Genomic_DNA.
DR   EMBL; CM002241; EAA31177.3; -; Genomic_DNA.
DR   RefSeq; XP_960413.3; XM_955320.3.
DR   AlphaFoldDB; Q7S6P8; -.
DR   SMR; Q7S6P8; -.
DR   STRING; 5141.EFNCRP00000004475; -.
DR   EnsemblFungi; EAA31177; EAA31177; NCU04787.
DR   GeneID; 3876588; -.
DR   KEGG; ncr:NCU04787; -.
DR   VEuPathDB; FungiDB:NCU04787; -.
DR   HOGENOM; CLU_018299_2_0_1; -.
DR   InParanoid; Q7S6P8; -.
DR   Proteomes; UP000001805; Chromosome 5, Linkage Group VI.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   InterPro; IPR025160; AATF.
DR   InterPro; IPR039223; AATF/Bfr2.
DR   InterPro; IPR012617; AATF_C.
DR   PANTHER; PTHR15565; PTHR15565; 2.
DR   Pfam; PF13339; AATF-Che1; 1.
DR   Pfam; PF08164; TRAUB; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..636
FT                   /note="Protein bfr2"
FT                   /id="PRO_0000056630"
FT   REGION          1..303
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        12..61
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        88..124
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..141
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        169..184
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        193..298
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   636 AA;  71634 MW;  32A7BE5B95057B33 CRC64;
     MPLYTTKKSN KLRASMFDEK PAKDYDPEAE PRDGDDDQSG SEADSDVERA ETEHYVTVGK
     SKLRKAEAPT LGPEYSGTRV SRKALEESDE EDFEDEEEDD EEDDDDEDDL EDGESETGSE
     EFADPDTADL ERDHIDEDAE ISSDNALGED DADWAEKFTF RGSSKPKTPA KTSKKDDLAV
     RIKKRPTAAD FMSGSEDDEE EEDDEEDLEE DEEDEEDSEE GEQNGLFDME AEETEDDEGE
     DDEEELDGAL LSGSDDEEGD SEEDDEDDEE GSGDEDEDED DEDEDEDEDD ESGDDDEKND
     VNAELRKIMA EDEKKIVSTF SKAAEADAQK GVAVRSQRRI FDSILNLRIR LQKALIAANT
     FNCVEKPENF KEKPYEAAEE AAVKLWNTID SVRNSFLPEQ VKAKAGEKRK RDAIELDTPA
     QEIWEVLEAV EGPANKYRRQ VLDKWSTRVR STTASMTKER RLAQSAGSQS LVSVLDDQLL
     SADRLIKKAR TPRSCAPAQA AKKVEEDADI YDDADFYQLL LKELVDQRSS DSAAPGESVA
     TVRWAALKEA KTRKQVDRKA SKGRKLRFTV HEKLQNFMAP EDRRSWEEHA IDRFFGTLFG
     QKMVLKEDEA EAEAAEEDEE MGGVNVEEAG LKLFRS