ID   BFR2_SCHPO              Reviewed;         452 AA.
AC   Q9US05;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Protein bfr2;
GN   Name=bfr2; ORFNames=SPAC664.08c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-31; SER-36 AND SER-37, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=18257517; DOI=10.1021/pr7006335;
RA   Wilson-Grady J.T., Villen J., Gygi S.P.;
RT   "Phosphoproteome analysis of fission yeast.";
RL   J. Proteome Res. 7:1088-1097(2008).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AATF family. {ECO:0000305}.
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DR   EMBL; CU329670; CAB65809.1; -; Genomic_DNA.
DR   PIR; T50238; T50238.
DR   RefSeq; NP_593456.1; NM_001018889.2.
DR   AlphaFoldDB; Q9US05; -.
DR   SMR; Q9US05; -.
DR   BioGRID; 279957; 6.
DR   STRING; 4896.SPAC664.08c.1; -.
DR   iPTMnet; Q9US05; -.
DR   MaxQB; Q9US05; -.
DR   PaxDb; Q9US05; -.
DR   PRIDE; Q9US05; -.
DR   EnsemblFungi; SPAC664.08c.1; SPAC664.08c.1:pep; SPAC664.08c.
DR   GeneID; 2543540; -.
DR   KEGG; spo:SPAC664.08c; -.
DR   PomBase; SPAC664.08c; bfr2.
DR   VEuPathDB; FungiDB:SPAC664.08c; -.
DR   eggNOG; KOG2773; Eukaryota.
DR   HOGENOM; CLU_018299_2_1_1; -.
DR   InParanoid; Q9US05; -.
DR   OMA; SKWDERT; -.
DR   PhylomeDB; Q9US05; -.
DR   PRO; PR:Q9US05; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005730; C:nucleolus; ISO:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   InterPro; IPR025160; AATF.
DR   InterPro; IPR039223; AATF/Bfr2.
DR   InterPro; IPR012617; AATF_C.
DR   PANTHER; PTHR15565; PTHR15565; 1.
DR   Pfam; PF13339; AATF-Che1; 1.
DR   Pfam; PF08164; TRAUB; 1.
PE   1: Evidence at protein level;
KW   Nucleus; Phosphoprotein; Reference proteome.
FT   CHAIN           1..452
FT                   /note="Protein bfr2"
FT                   /id="PRO_0000056631"
FT   REGION          1..141
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        39..75
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        76..92
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        93..107
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         31
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
FT   MOD_RES         36
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
FT   MOD_RES         37
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
SQ   SEQUENCE   452 AA;  51566 MW;  6E7E070EF670620E CRC64;
     MGKVSLKDEL AGMLNPQPQE RDPEALEDAF SDREDSSEEE NDTLGREHYV DVSESKLRSK
     QAPQLDPKFK GRKTSRQELL NSGSLNSQSS SPSEEEDSEE DENDAVSEDH ENFSSSEASS
     ISEENEDDDQ SSAIPEKDMD RLKKIINGEK KLSDQIRTSA LEDMKKGLAL KEQMRFYDNV
     LDTRIRLQKG CSQLLSSSNQ LQGDKVEARD GLVSFIQHTL QLRKNLLIDS GVEILDSRSK
     RKENPVSLEE IALEMNNLDD SLNEWKNDTL TKWHNRVQAV QGISQSNKFK ALNQSIVQQI
     ENSMINKKDL VERTRIDYSD PNNKTFNPEI YNDTDFYQSL LKDFINSRMA DSTRDGTVRW
     MATKKQKQKK ENVDTKASKG RKIRYHVHDK LQNFMAPIEV TVWPDEQTED LFSSLLGQQL
     DLSETANDTN TSNFVEKDDE LISSNDGFSL FG