SEC17_ASHGO
ID SEC17_ASHGO Reviewed; 291 AA.
AC Q75D68;
DT 01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 93.
DE RecName: Full=Vesicular-fusion protein SEC17;
GN Name=SEC17; OrderedLocusNames=ABR155C;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Required for vesicular transport between the endoplasmic
CC reticulum and the Golgi apparatus. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Peripheral membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SNAP family. {ECO:0000305}.
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DR EMBL; AE016815; AAS50927.1; -; Genomic_DNA.
DR RefSeq; NP_983103.1; NM_208456.1.
DR AlphaFoldDB; Q75D68; -.
DR SMR; Q75D68; -.
DR STRING; 33169.AAS50927; -.
DR EnsemblFungi; AAS50927; AAS50927; AGOS_ABR155C.
DR GeneID; 4619213; -.
DR KEGG; ago:AGOS_ABR155C; -.
DR eggNOG; KOG1586; Eukaryota.
DR HOGENOM; CLU_046329_0_2_1; -.
DR InParanoid; Q75D68; -.
DR OMA; WSVKEYL; -.
DR Proteomes; UP000000591; Chromosome II.
DR GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR GO; GO:0019898; C:extrinsic component of membrane; IEA:EnsemblFungi.
DR GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR GO; GO:0001671; F:ATPase activator activity; IEA:EnsemblFungi.
DR GO; GO:0005483; F:soluble NSF attachment protein activity; IBA:GO_Central.
DR GO; GO:0019905; F:syntaxin binding; IBA:GO_Central.
DR GO; GO:0006914; P:autophagy; IEA:EnsemblFungi.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0035494; P:SNARE complex disassembly; IBA:GO_Central.
DR GO; GO:0042144; P:vacuole fusion, non-autophagic; IEA:EnsemblFungi.
DR GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:EnsemblFungi.
DR CDD; cd15832; SNAP; 1.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR000744; NSF_attach.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR13768; PTHR13768; 1.
DR PRINTS; PR00448; NSFATTACHMNT.
DR SUPFAM; SSF48452; SSF48452; 1.
PE 3: Inferred from homology;
KW ER-Golgi transport; Membrane; Protein transport; Reference proteome;
KW Transport.
FT CHAIN 1..291
FT /note="Vesicular-fusion protein SEC17"
FT /id="PRO_0000219071"
SQ SEQUENCE 291 AA; 32885 MW; 569BE3FF58A2F48E CRC64;
MSEAKDLIAR AEKKAQPASG LMKWLTGGDS YRLEEASDLY VEAANLYRLS KELSAAGDTF
WKAAECQVEA GNEDEAGNTF VEAYKCYKGA NPERACEALE RAIAIFTRKG QFRRGAYFKF
ELAEVQETDL QDYGRARENY ELAGDWYMQD QALALSNKAY IKCADLNALD EKYLAAAELY
RKIISNSVGN RLSQWSLRDY YLKLCLCFLA ASDTVAAEKT LQEALQEDSS FHGSREHDLL
AAIIEDVKQG DVEAFSNHVF EFDKFSKLDK WKTTVLLRVK TSITEVEDDL L
