ID   SEC17_KOMPG             Reviewed;         297 AA.
AC   Q9P4D0; C4R1B4;
DT   29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 2.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Vesicular-fusion protein SEC17;
GN   Name=SEC17; OrderedLocusNames=PAS_chr2-1_0644;
OS   Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Phaffomycetaceae; Komagataella.
OX   NCBI_TaxID=644223;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10923020;
RX   DOI=10.1002/1097-0061(200008)16:11<979::aid-yea594>3.0.co;2-c;
RA   Payne W.E., Kaiser C.A., Bevis B.J., Soderholm J., Fu D., Sears I.B.,
RA   Glick B.S.;
RT   "Isolation of Pichia pastoris genes involved in ER-to-Golgi transport.";
RL   Yeast 16:979-993(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS115 / ATCC 20864;
RX   PubMed=19465926; DOI=10.1038/nbt.1544;
RA   De Schutter K., Lin Y.-C., Tiels P., Van Hecke A., Glinka S.,
RA   Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT   "Genome sequence of the recombinant protein production host Pichia
RT   pastoris.";
RL   Nat. Biotechnol. 27:561-566(2009).
CC   -!- FUNCTION: Required for vesicular transport between the endoplasmic
CC       reticulum and the Golgi apparatus. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SNAP family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF27632.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; AF216957; AAF27632.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; FN392320; CAY69288.1; -; Genomic_DNA.
DR   RefSeq; XP_002491568.1; XM_002491523.1.
DR   AlphaFoldDB; Q9P4D0; -.
DR   SMR; Q9P4D0; -.
DR   STRING; 644223.Q9P4D0; -.
DR   EnsemblFungi; CAY69288; CAY69288; PAS_chr2-1_0644.
DR   GeneID; 8199258; -.
DR   KEGG; ppa:PAS_chr2-1_0644; -.
DR   eggNOG; KOG1586; Eukaryota.
DR   HOGENOM; CLU_046329_0_2_1; -.
DR   InParanoid; Q9P4D0; -.
DR   OMA; WSVKEYL; -.
DR   Proteomes; UP000000314; Chromosome 2.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR   CDD; cd15832; SNAP; 1.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR000744; NSF_attach.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR13768; PTHR13768; 1.
DR   PRINTS; PR00448; NSFATTACHMNT.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   3: Inferred from homology;
KW   ER-Golgi transport; Membrane; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..297
FT                   /note="Vesicular-fusion protein SEC17"
FT                   /id="PRO_0000219074"
FT   CONFLICT        106
FT                   /note="F -> L (in Ref. 1; AAF27632)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        215
FT                   /note="D -> G (in Ref. 1; AAF27632)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        238
FT                   /note="E -> G (in Ref. 1; AAF27632)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        294..297
FT                   /note="DDLT -> MI (in Ref. 1; AAF27632)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   297 AA;  33321 MW;  1D4CE0EBEC840039 CRC64;
     MSEAEQLIAK ADKKCAPVSG FASFFSGSGS YRFEEAADLY TQAANLYRIQ RKSNKAGHVF
     EKAADAQIKA DSKDEAANSL IEAYKCYKLD APSDAARCLN KAVEFFALKG QFRRGANFKA
     ELAELYETKM ADPKHAILAY EEAGEWYRGD SAEALANKCY VKAADLSCSD EVQDFLKAAE
     SYERIAKESL NNSLAKWSLK DYFFKAILCR LALNDYPSAS ALLERFVSWD PTFEKTREYE
     FALKLVDGLK EGDPDIIASA SHEYDQISRL DNFKVKILNK IKNNIRDSDD LAEDDLT