SEC17_NEUCR
ID SEC17_NEUCR Reviewed; 292 AA.
AC Q9P6A5; Q7RY28;
DT 29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 99.
DE RecName: Full=Probable vesicular-fusion protein sec17 homolog;
GN ORFNames=B1D1.150, NCU01674;
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX PubMed=12655011; DOI=10.1093/nar/gkg293;
RA Mannhaupt G., Montrone C., Haase D., Mewes H.-W., Aign V., Hoheisel J.D.,
RA Fartmann B., Nyakatura G., Kempken F., Maier J., Schulte U.;
RT "What's in the genome of a filamentous fungus? Analysis of the Neurospora
RT genome sequence.";
RL Nucleic Acids Res. 31:1944-1954(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
CC -!- FUNCTION: Required for vesicular transport between the endoplasmic
CC reticulum and the Golgi apparatus. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Peripheral membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SNAP family. {ECO:0000305}.
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DR EMBL; AL355927; CAB91264.1; -; Genomic_DNA.
DR EMBL; CM002237; EAA27644.2; -; Genomic_DNA.
DR PIR; T49361; T49361.
DR RefSeq; XP_956880.2; XM_951787.3.
DR AlphaFoldDB; Q9P6A5; -.
DR SMR; Q9P6A5; -.
DR STRING; 5141.EFNCRP00000001724; -.
DR EnsemblFungi; EAA27644; EAA27644; NCU01674.
DR GeneID; 3873042; -.
DR KEGG; ncr:NCU01674; -.
DR VEuPathDB; FungiDB:NCU01674; -.
DR HOGENOM; CLU_046329_1_0_1; -.
DR InParanoid; Q9P6A5; -.
DR Proteomes; UP000001805; Chromosome 6, Linkage Group II.
DR GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR GO; GO:0005483; F:soluble NSF attachment protein activity; IBA:GO_Central.
DR GO; GO:0019905; F:syntaxin binding; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0035494; P:SNARE complex disassembly; IBA:GO_Central.
DR CDD; cd15832; SNAP; 1.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR000744; NSF_attach.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR13768; PTHR13768; 1.
DR PRINTS; PR00448; NSFATTACHMNT.
DR SUPFAM; SSF48452; SSF48452; 1.
PE 3: Inferred from homology;
KW ER-Golgi transport; Membrane; Protein transport; Reference proteome;
KW Transport.
FT CHAIN 1..292
FT /note="Probable vesicular-fusion protein sec17 homolog"
FT /id="PRO_0000219073"
SQ SEQUENCE 292 AA; 32805 MW; C9BD75D8128E19E7 CRC64;
MAVDPRVLQQ EAEKTLASAS KGWGLFGNKE DKYQNAADQY IQAANAFRLQ KSNTEAGKCF
EEAAKIFTEK LKEPNDAANA MLDAFKVYRK DAPDNAVRCV EVAIKQYTMA GNFRRAASHK
ENQAEVYENE LQNKPEAIKA YTTAAEWYEN DGAVALANKL WLKVADLSAL AGDFFAAIEK
FEKVAEASLG NNLMRYSVKE YFLKAGLCSL ATKDMVTAQR NITKYAEKDP SFTGQREYQL
LVDLLEAASN NNLEMFQDKL AAYDKMSRLD DWKAAVLLQI KNNFEEADNE FS