ID   SEC17_SCHPO             Reviewed;         289 AA.
AC   Q9P4X4;
DT   29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Probable vesicular-fusion protein sec17 homolog;
GN   Name=sec17; ORFNames=SPAC959.02;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-76, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY.
RX   PubMed=18257517; DOI=10.1021/pr7006335;
RA   Wilson-Grady J.T., Villen J., Gygi S.P.;
RT   "Phosphoproteome analysis of fission yeast.";
RL   J. Proteome Res. 7:1088-1097(2008).
CC   -!- FUNCTION: Required for vesicular transport between the endoplasmic
CC       reticulum and the Golgi apparatus. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SNAP family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU329670; CAB93009.1; -; Genomic_DNA.
DR   RefSeq; NP_594169.1; NM_001019593.2.
DR   AlphaFoldDB; Q9P4X4; -.
DR   SMR; Q9P4X4; -.
DR   BioGRID; 279908; 1.
DR   STRING; 4896.SPAC959.02.1; -.
DR   iPTMnet; Q9P4X4; -.
DR   MaxQB; Q9P4X4; -.
DR   PaxDb; Q9P4X4; -.
DR   PRIDE; Q9P4X4; -.
DR   EnsemblFungi; SPAC959.02.1; SPAC959.02.1:pep; SPAC959.02.
DR   GeneID; 2543488; -.
DR   KEGG; spo:SPAC959.02; -.
DR   PomBase; SPAC959.02; sec17.
DR   VEuPathDB; FungiDB:SPAC959.02; -.
DR   eggNOG; KOG1586; Eukaryota.
DR   HOGENOM; CLU_046329_0_2_1; -.
DR   InParanoid; Q9P4X4; -.
DR   OMA; WSVKEYL; -.
DR   PhylomeDB; Q9P4X4; -.
DR   Reactome; R-SPO-204005; COPII-mediated vesicle transport.
DR   Reactome; R-SPO-6807878; COPI-mediated anterograde transport.
DR   Reactome; R-SPO-6811434; COPI-dependent Golgi-to-ER retrograde traffic.
DR   Reactome; R-SPO-6811438; Intra-Golgi traffic.
DR   Reactome; R-SPO-6811440; Retrograde transport at the Trans-Golgi-Network.
DR   PRO; PR:Q9P4X4; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR   GO; GO:0005483; F:soluble NSF attachment protein activity; ISO:PomBase.
DR   GO; GO:0019905; F:syntaxin binding; IBA:GO_Central.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; ISO:PomBase.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR   GO; GO:0035494; P:SNARE complex disassembly; IBA:GO_Central.
DR   GO; GO:0042144; P:vacuole fusion, non-autophagic; ISO:PomBase.
DR   CDD; cd15832; SNAP; 1.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR000744; NSF_attach.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR13768; PTHR13768; 1.
DR   PRINTS; PR00448; NSFATTACHMNT.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   1: Evidence at protein level;
KW   ER-Golgi transport; Membrane; Phosphoprotein; Protein transport;
KW   Reference proteome; Transport.
FT   CHAIN           1..289
FT                   /note="Probable vesicular-fusion protein sec17 homolog"
FT                   /id="PRO_0000219075"
FT   MOD_RES         76
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
SQ   SEQUENCE   289 AA;  32222 MW;  E4179D04465F5C64 CRC64;
     MIADPDQLMQ KAAKKAQGTG GFALFGGGNK YDEASELFLD AANGYRLQKQ GSAAGYAFEK
     AAEMQLKTDD KDDAASTYVE AFKSYRREKP SEAARVLQIA IELFTRRGNF RRAANYKMDL
     GDIFEQELQD TKAALGAYED AGEWYSSDQA DALANKAYLK AADLAGLCGE YSLAIRKFEQ
     VARASVQNNL LKWSVKDYLL KAGLCYMANG DEIATRRALE HFLEIDPSFA STREYQLLKD
     LQDTIEASDA NMFADKVFTY DQLSKLDSWK TTILLKIKSS IQEAEDDLT