SEC1B_ARATH
ID SEC1B_ARATH Reviewed; 662 AA.
AC Q9SZ77;
DT 01-FEB-2003, integrated into UniProtKB/Swiss-Prot.
DT 03-MAY-2011, sequence version 3.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Protein transport Sec1b;
DE Short=AtSec1b;
GN Name=SEC1B; OrderedLocusNames=At4g12120; ORFNames=F16J13.190;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the vesicle trafficking. Binds syntaxins (By
CC similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the STXBP/unc-18/SEC1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB40953.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB78255.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL049638; CAB40953.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161533; CAB78255.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE83098.1; -; Genomic_DNA.
DR EMBL; AY088783; AAM67096.1; -; mRNA.
DR RefSeq; NP_567388.1; NM_117282.3.
DR AlphaFoldDB; Q9SZ77; -.
DR SMR; Q9SZ77; -.
DR BioGRID; 12118; 1.
DR STRING; 3702.AT4G12120.1; -.
DR iPTMnet; Q9SZ77; -.
DR PaxDb; Q9SZ77; -.
DR PRIDE; Q9SZ77; -.
DR ProteomicsDB; 232828; -.
DR EnsemblPlants; AT4G12120.1; AT4G12120.1; AT4G12120.
DR GeneID; 826820; -.
DR Gramene; AT4G12120.1; AT4G12120.1; AT4G12120.
DR KEGG; ath:AT4G12120; -.
DR Araport; AT4G12120; -.
DR TAIR; locus:2118126; AT4G12120.
DR eggNOG; KOG1300; Eukaryota.
DR HOGENOM; CLU_009210_3_0_1; -.
DR InParanoid; Q9SZ77; -.
DR OMA; SSCKMSE; -.
DR OrthoDB; 725424at2759; -.
DR PRO; PR:Q9SZ77; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9SZ77; baseline and differential.
DR Genevisible; Q9SZ77; AT.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0030141; C:secretory granule; IBA:GO_Central.
DR GO; GO:0019905; F:syntaxin binding; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0006904; P:vesicle docking involved in exocytosis; IBA:GO_Central.
DR GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR Gene3D; 3.40.50.1910; -; 2.
DR Gene3D; 3.40.50.2060; -; 1.
DR Gene3D; 3.90.830.10; -; 1.
DR InterPro; IPR043154; Sec-1-like_dom1.
DR InterPro; IPR043127; Sec-1-like_dom3a.
DR InterPro; IPR001619; Sec1-like.
DR InterPro; IPR027482; Sec1-like_dom2.
DR InterPro; IPR036045; Sec1-like_sf.
DR PANTHER; PTHR11679; PTHR11679; 1.
DR Pfam; PF00995; Sec1; 1.
DR PIRSF; PIRSF005715; VPS45_Sec1; 1.
DR SUPFAM; SSF56815; SSF56815; 1.
PE 2: Evidence at transcript level;
KW Protein transport; Reference proteome; Transport.
FT CHAIN 1..662
FT /note="Protein transport Sec1b"
FT /id="PRO_0000206296"
FT CONFLICT 14
FT /note="E -> D (in Ref. 3; AAM67096)"
FT /evidence="ECO:0000305"
FT CONFLICT 68
FT /note="E -> G (in Ref. 3; AAM67096)"
FT /evidence="ECO:0000305"
FT CONFLICT 131
FT /note="L -> V (in Ref. 3; AAM67096)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 662 AA; 75418 MW; 9D6EB17203385FAF CRC64;
MSFSDSGSSS YGGEYKNFRQ ITRERLLCEM LRPERNGSSK LTWKVLVMDK FTVKIMSSAC
KMSEITQEGI SLVEVITKHR QPMTAMEVIY FIQPTEENVT AFLSDMTGKS PLYKKAFVFF
SSPVSRSLVN LIKKDMRAMK RIGGLKEMNL EYISMDIQGF VTNNENALEE LFCDDENHQR
ADACLNVVAK RIATVLASLK EYPFVRYRGA KALDATTMTT YRELIPTKLA ASVWNCLARY
KQTIEDFPQT ETCELLILDR SIDQIAPLIH EWTYDAMCHD LLNMEGNKYT HEVPSKTGDK
PEKKEVLLDE EDSIWVELRD AHIADASERL HEKMTNFVSK NKAAQLKHSS KDFGDLSSKD
LQKMVHALPQ YSEQIDKLSL HVEIARTINR TIMEQGLRDL GQLEQDLVFG DAGRKDVIKF
LSTNHIISHE SKLRLIMIVA AIYPKKFEGE KGRKMMELAK LSGDDVVAVN NMRLLGPVHT
ECKKSTTGSF PLKFDVLKTK RAARRDRVGE TQTWQLSRFY PIVEELVEKL SKGHLPKQDY
PCMNEPKPTF YSGSLSPSAS PVLPHSRRTP TWARRHLSDD GYFSDSVLGR ASSGFKRKGQ
RIFVFIVGGA TRSELRVCHK LTEKLDREVI LGSSSFLDPL TFLTKMKQLN EEEEISLDDI
VI
