ID   SEC39_SCHPO             Reviewed;         769 AA.
AC   O14266;
DT   02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Protein transport protein sec39;
GN   Name=sec39 {ECO:0000250|UniProtKB:Q12745}; ORFNames=SPAC7D4.11c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1] {ECO:0000312|EMBL:CAB16728.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Required for protein transport between the Golgi and the
CC       endoplasmic reticulum. May contribute to tethering of coatomer-coated
CC       retrograde transport vesicles to the ER membrane through interaction
CC       with and stabilization of the SNARE complex (By similarity).
CC       {ECO:0000250|UniProtKB:Q12745}.
CC   -!- SUBUNIT: Component of a peripheral membrane protein complex consisting
CC       of dsl1, sec39 and tip20. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SEC39 family. {ECO:0000305}.
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DR   EMBL; CU329670; CAB16728.1; -; Genomic_DNA.
DR   PIR; T39089; T39089.
DR   RefSeq; NP_593847.1; NM_001019276.2.
DR   AlphaFoldDB; O14266; -.
DR   STRING; 4896.SPAC7D4.11c.1; -.
DR   MaxQB; O14266; -.
DR   PaxDb; O14266; -.
DR   EnsemblFungi; SPAC7D4.11c.1; SPAC7D4.11c.1:pep; SPAC7D4.11c.
DR   GeneID; 2541492; -.
DR   KEGG; spo:SPAC7D4.11c; -.
DR   PomBase; SPAC7D4.11c; sec39.
DR   VEuPathDB; FungiDB:SPAC7D4.11c; -.
DR   eggNOG; ENOG502RS09; Eukaryota.
DR   HOGENOM; CLU_375595_0_0_1; -.
DR   InParanoid; O14266; -.
DR   OMA; AWRRCDE; -.
DR   PRO; PR:O14266; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0070939; C:Dsl1/NZR complex; IBA:GO_Central.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; ISO:PomBase.
DR   GO; GO:0031965; C:nuclear membrane; ISO:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR   GO; GO:0006886; P:intracellular protein transport; NAS:PomBase.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; ISO:PomBase.
DR   InterPro; IPR013244; Sec39_domain.
DR   Pfam; PF08314; Sec39; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; ER-Golgi transport; Membrane; Protein transport;
KW   Reference proteome; Transport.
FT   CHAIN           1..769
FT                   /note="Protein transport protein sec39"
FT                   /id="PRO_0000234108"
SQ   SEQUENCE   769 AA;  87511 MW;  75BCC09B91817D23 CRC64;
     MNEDKLESKW LFSLTESQKL YLLISLIINK KLPEAKFVYK LLDYTKGNWL SLLLRFLPET
     TDPECYIPYI DIDSHYGNIK ASVNDIEPIV LPDEELCQLR LTNMKLWNCK LPSLKDEAEF
     YSLFSKKIVE ETDLVDLAYQ LTKNSQAPAE IQQWNSGTFT VFHKLSQFAA VPINLEEMEA
     ATIRDVISLA FPVLDSKNCV FIMDEIITVF INNSSNDPNL ISENWDFVWK KLLQLVKTDG
     LAVVHTLVLN WNTIEPKLFL KLAKVALASC YISDDSSLYS VSLARDITEA IQNKLNFSDV
     NFGDLLKKPH DFSADGLLSL QNDLTTPSSL STSLLMEITK AIALLTQLKV PAPTFKTSVS
     ISCSNFDSQI KYLENVLLNA LGTIQSPDYK DWHDLYSYIE RFKQLSLFFL NISEDAISVV
     FLKQMLQEKS FLALKQMRNE IGLKDIEPKV LIDCLKTSFY ENFRAASNMN KNRGKLALAC
     KVLDVFVDCE PTIDLRRRLN SLVNACSLIQ PFKLILEPGK PLSPSLVEAN LNPDKLIKTI
     FSQNPSAYTL YDDILALDIE LHKAAGDFDY SQVFTELRRI TEHMITLTID VSLEKDDIEY
     AKQIVEDRLM TLAEASEDVK FFLYEIAYKI GKFPSNHPNA KVIRLDMLQI AIANAPRQKL
     DEVVSYWTDF QSNSKVLEEN LNTTDVEFHS SKKIKDYEDL EDANFDEEWS KAADLMSDDP
     ENQVLYEGNL NSSLSLNEDP SVSDENLTQK VTSKLTNGLG WVLGVPPRK