ID   SEC62_CANAL             Reviewed;         293 AA.
AC   Q5AI21; A0A1D8PD09;
DT   24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Translocation protein SEC62;
GN   Name=SEC62; OrderedLocusNames=CAALFM_C103340CA;
GN   ORFNames=CaO19.10549, CaO19.3031;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Required for preprotein translocation. {ECO:0000250}.
CC   -!- SUBUNIT: Part of a complex that contains SEC61, SEC62, SEC63, SEC66 and
CC       SEC72. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SEC62 family. {ECO:0000305}.
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DR   EMBL; CP017623; AOW26015.1; -; Genomic_DNA.
DR   RefSeq; XP_721529.1; XM_716436.2.
DR   AlphaFoldDB; Q5AI21; -.
DR   SMR; Q5AI21; -.
DR   STRING; 237561.Q5AI21; -.
DR   PRIDE; Q5AI21; -.
DR   GeneID; 3636860; -.
DR   KEGG; cal:CAALFM_C103340CA; -.
DR   CGD; CAL0000199574; SEC62.
DR   VEuPathDB; FungiDB:C1_03340C_A; -.
DR   eggNOG; KOG2927; Eukaryota.
DR   HOGENOM; CLU_040936_1_0_1; -.
DR   InParanoid; Q5AI21; -.
DR   OMA; FKPLYGW; -.
DR   OrthoDB; 1474000at2759; -.
DR   PRO; PR:Q5AI21; -.
DR   Proteomes; UP000000559; Chromosome 1.
DR   GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR   GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IDA:CGD.
DR   GO; GO:0031204; P:post-translational protein targeting to membrane, translocation; IBA:GO_Central.
DR   InterPro; IPR004728; Sec62.
DR   InterPro; IPR011553; Sec62_asco.
DR   PANTHER; PTHR12443; PTHR12443; 1.
DR   Pfam; PF03839; Sec62; 1.
DR   TIGRFAMs; TIGR00869; sec62; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Protein transport; Reference proteome;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..293
FT                   /note="Translocation protein SEC62"
FT                   /id="PRO_0000206621"
FT   TOPO_DOM        1..150
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        151..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        172..185
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        207..293
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          240..293
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        240..261
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        265..284
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   293 AA;  33286 MW;  B4CC4BBA36824ED0 CRC64;
     MSAPTPPQTG QFQVATSAQR SPVAVNIVNY LFQNPILKQR TGLLDNTNDI EFFRFKRLQR
     ALLSDDYKQK QQNPKNGLIP VANNEDVQKV FVLLIQNQLL LPLQKLHYAE VKAVKGWKPN
     KEKPTLKRAD KAVMDPDVYY GWLYQKPNPY ILLYSFLAIA GVFAVILFPL WPNFMKRGVW
     YLSMGALGLI ALFFATAIVR LIIYIISLVA FPKPFWLFPN LFEDCGVIES FQPVYAWEEP
     KKKKGKKKKE PKLEVVEEKV GSSSGDVKVT GSELSNGSST TGKRKVTLEE VEE