ID   SEC62_CANGA             Reviewed;         257 AA.
AC   Q6FRU9;
DT   24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Translocation protein SEC62;
GN   Name=SEC62; OrderedLocusNames=CAGL0H05731g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for preprotein translocation. {ECO:0000250}.
CC   -!- SUBUNIT: Part of a complex that contains SEC61, SEC62, SEC63, SEC66 and
CC       SEC72. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SEC62 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR380954; CAG59978.1; -; Genomic_DNA.
DR   RefSeq; XP_447045.1; XM_447045.1.
DR   AlphaFoldDB; Q6FRU9; -.
DR   SMR; Q6FRU9; -.
DR   STRING; 5478.XP_447045.1; -.
DR   PRIDE; Q6FRU9; -.
DR   EnsemblFungi; CAG59978; CAG59978; CAGL0H05731g.
DR   GeneID; 2888597; -.
DR   KEGG; cgr:CAGL0H05731g; -.
DR   CGD; CAL0130526; CAGL0H05731g.
DR   VEuPathDB; FungiDB:CAGL0H05731g; -.
DR   eggNOG; KOG2927; Eukaryota.
DR   HOGENOM; CLU_040936_1_0_1; -.
DR   InParanoid; Q6FRU9; -.
DR   OMA; FKPLYGW; -.
DR   Proteomes; UP000002428; Chromosome H.
DR   GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IEA:InterPro.
DR   GO; GO:0031207; C:Sec62/Sec63 complex; IEA:EnsemblFungi.
DR   GO; GO:0071256; C:translocon complex; IEA:EnsemblFungi.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; IEA:EnsemblFungi.
DR   GO; GO:0031204; P:post-translational protein targeting to membrane, translocation; IEA:EnsemblFungi.
DR   InterPro; IPR004728; Sec62.
DR   InterPro; IPR011553; Sec62_asco.
DR   PANTHER; PTHR12443; PTHR12443; 1.
DR   Pfam; PF03839; Sec62; 1.
DR   TIGRFAMs; TIGR00869; sec62; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Protein transport; Reference proteome;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..257
FT                   /note="Translocation protein SEC62"
FT                   /id="PRO_0000206622"
FT   TOPO_DOM        1..137
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        138..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        159..170
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        171..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        192..257
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   257 AA;  30095 MW;  8DC6C5B4680B5D88 CRC64;
     MDQSAVLAIA SFVRNRSELK ARKGLFQDKP TDFFRYKRFV RCLKSDAYKK KSLKQPDLYP
     PLPEDEEKFA ELARGIFVEF IKNQLVVPGQ KLHSYECKEH GLKPSKDYPH LIMSTKATLD
     DNEYYLWHYN PKTLTDYLIV FGVIGVILAF VCYPLWPASM RRGTYYLSLA AFGFLGVFFG
     VAIIRLIVFL ISMLFIREKG GFWLFPNLFE DCGFFDSFKP LYGFGDKETY TYIKKMKKQK
     KRQAKKEKLK KLKEKAN