ID   SEC62_CHICK             Reviewed;         398 AA.
AC   Q5F3A1;
DT   24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Translocation protein SEC62;
DE   AltName: Full=Translocation protein 1;
DE            Short=TP-1;
GN   Name=SEC62; Synonyms=TLOC1; ORFNames=RCJMB04_25p9;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Required for preprotein translocation. {ECO:0000250}.
CC   -!- SUBUNIT: Part of a complex that contains SEC61, SEC62 and SEC63.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SEC62 family. {ECO:0000305}.
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DR   EMBL; AJ851749; CAH65383.1; -; mRNA.
DR   RefSeq; NP_001012620.1; NM_001012602.1.
DR   AlphaFoldDB; Q5F3A1; -.
DR   SMR; Q5F3A1; -.
DR   STRING; 9031.ENSGALP00000015260; -.
DR   PaxDb; Q5F3A1; -.
DR   Ensembl; ENSGALT00000015276; ENSGALP00000015260; ENSGALG00000009379.
DR   GeneID; 424993; -.
DR   KEGG; gga:424993; -.
DR   CTD; 7095; -.
DR   VEuPathDB; HostDB:geneid_424993; -.
DR   eggNOG; KOG2927; Eukaryota.
DR   GeneTree; ENSGT00390000002757; -.
DR   HOGENOM; CLU_051910_0_0_1; -.
DR   InParanoid; Q5F3A1; -.
DR   OMA; HQEQSFN; -.
DR   OrthoDB; 1474000at2759; -.
DR   PhylomeDB; Q5F3A1; -.
DR   TreeFam; TF314944; -.
DR   PRO; PR:Q5F3A1; -.
DR   Proteomes; UP000000539; Chromosome 9.
DR   Bgee; ENSGALG00000009379; Expressed in ovary and 14 other tissues.
DR   GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR   GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0031204; P:post-translational protein targeting to membrane, translocation; IBA:GO_Central.
DR   InterPro; IPR004728; Sec62.
DR   PANTHER; PTHR12443; PTHR12443; 1.
DR   Pfam; PF03839; Sec62; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; Membrane; Protein transport; Reference proteome;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..398
FT                   /note="Translocation protein SEC62"
FT                   /id="PRO_0000206619"
FT   TOPO_DOM        1..196
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        197..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        218..234
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        235..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        256..398
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          101..167
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          289..398
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        289..328
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        336..358
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        375..389
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   398 AA;  45966 MW;  E8EA595FBC3E9949 CRC64;
     MAERRRHRKR IQEVGEPFKE EKAVAKYLRF NCPTKSTNMM GHRVDYFIAS KAVDCLLDSK
     WAKAKKGEEA LFTTRESVVD YCNRLLKKQF FHRALKVMKM KPDKDTKKEK EKGKAESGKE
     EEKKSKKESS KDEKTKKEKE KKKDGEKEEC KKDETPGTPK KKETKRKFKL EPHEDQVFLD
     GNEVYVWIYD PVHFKTFAMG LVLVIAVIAA TLFPLWPAEM RVGVYYLSVG AGCFVASILL
     LAVARCILFL IIWLITGGRH HFWFLPNLTA DVGFIDSFRP LYTHEYKGPK ADLKKEEKSE
     SKKQQKYDSE EKSDSEKKEE EDGKTEATRN SGTEGSGGER HSDTDSDRRE DDRSQHSSGN
     GNDFEMITKE ELEQQTDEGD CEEDEDEDTE SRPSHEKS