ID   SEC62_DEBHA             Reviewed;         278 AA.
AC   Q6BI99;
DT   24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Translocation protein SEC62;
GN   Name=SEC62; OrderedLocusNames=DEHA2G12386g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for preprotein translocation. {ECO:0000250}.
CC   -!- SUBUNIT: Part of a complex that contains SEC61, SEC62, SEC63, SEC66 and
CC       SEC72. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SEC62 family. {ECO:0000305}.
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DR   EMBL; CR382139; CAG90558.1; -; Genomic_DNA.
DR   RefSeq; XP_462072.1; XM_462072.1.
DR   AlphaFoldDB; Q6BI99; -.
DR   SMR; Q6BI99; -.
DR   STRING; 4959.XP_462072.1; -.
DR   EnsemblFungi; CAG90558; CAG90558; DEHA2G12386g.
DR   GeneID; 2904983; -.
DR   KEGG; dha:DEHA2G12386g; -.
DR   VEuPathDB; FungiDB:DEHA2G12386g; -.
DR   eggNOG; KOG2927; Eukaryota.
DR   HOGENOM; CLU_040936_1_0_1; -.
DR   InParanoid; Q6BI99; -.
DR   OMA; GLWLYPN; -.
DR   OrthoDB; 1474000at2759; -.
DR   Proteomes; UP000000599; Chromosome G.
DR   GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR004728; Sec62.
DR   InterPro; IPR011553; Sec62_asco.
DR   PANTHER; PTHR12443; PTHR12443; 1.
DR   Pfam; PF03839; Sec62; 1.
DR   TIGRFAMs; TIGR00869; sec62; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Protein transport; Reference proteome;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..278
FT                   /note="Translocation protein SEC62"
FT                   /id="PRO_0000206623"
FT   TOPO_DOM        1..142
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        164..178
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        179..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        200..278
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          230..278
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        231..245
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   278 AA;  31683 MW;  5584D810A339ABD9 CRC64;
     MAEVPITTSN QRSQVAINIA NYLKDNKILK QRTGLLNNSE DVEFFRYKRL ARALLSDDYK
     TKQANHKNGL IPIADEQEAA KVFITLIQSQ FVIPVEKLHY NEIKQANKSW KPNKTKPTLK
     QSTKANIEPN AYFVWTYNKP NPFILLYSIL LLVGIFTIIL FPLWPNFMKI GVWYLSMGLL
     GLLGLFFLIA IIRLIIYIIT LLVLPRAFWL YPNLFEDCGV LESFQPLYGW DEPKKSKKGK
     SSKSASKPET ESSGAATGVK PAENAPTKRK VVLEEVDE