ID   SEC65_CANGA             Reviewed;         264 AA.
AC   Q6FP52;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Signal recognition particle SEC65 subunit;
GN   Name=SEC65; OrderedLocusNames=CAGL0J06578g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Signal-recognition-particle assembly has a crucial role in
CC       targeting secretory proteins to the rough endoplasmic reticulum
CC       membrane. It must be involved intimately in the translocation of a wide
CC       variety of protein substrates (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Fungal signal recognition particle consists of a 7S RNA
CC       molecule (scR1) and at least six protein subunits: SRP72, SRP68, SRP54,
CC       SEC65, SRP21 and SRP14. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SRP19 family. {ECO:0000305}.
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DR   EMBL; CR380956; CAG60943.1; -; Genomic_DNA.
DR   RefSeq; XP_447992.1; XM_447992.1.
DR   AlphaFoldDB; Q6FP52; -.
DR   SMR; Q6FP52; -.
DR   STRING; 5478.XP_447992.1; -.
DR   EnsemblFungi; CAG60943; CAG60943; CAGL0J06578g.
DR   GeneID; 2889544; -.
DR   KEGG; cgr:CAGL0J06578g; -.
DR   CGD; CAL0133700; CAGL0J06578g.
DR   VEuPathDB; FungiDB:CAGL0J06578g; -.
DR   eggNOG; KOG3198; Eukaryota.
DR   HOGENOM; CLU_065433_1_1_1; -.
DR   InParanoid; Q6FP52; -.
DR   OMA; KVKGFKM; -.
DR   Proteomes; UP000002428; Chromosome J.
DR   GO; GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IEA:UniProtKB-KW.
DR   GO; GO:0008312; F:7S RNA binding; IEA:EnsemblFungi.
DR   GO; GO:0006617; P:SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition; IEA:EnsemblFungi.
DR   Gene3D; 3.30.56.30; -; 1.
DR   InterPro; IPR002778; Signal_recog_particle_SRP19.
DR   InterPro; IPR036521; SRP19-like_sf.
DR   PANTHER; PTHR17453; PTHR17453; 1.
DR   Pfam; PF01922; SRP19; 1.
DR   SUPFAM; SSF69695; SSF69695; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Ribonucleoprotein; RNA-binding;
KW   Signal recognition particle.
FT   CHAIN           1..264
FT                   /note="Signal recognition particle SEC65 subunit"
FT                   /id="PRO_0000135206"
SQ   SEQUENCE   264 AA;  30334 MW;  07C8B6D556E1D61C CRC64;
     MPKLEEIEDY DDIDNMDMDL AELDPTLNTP IAPKITPTVV RSQDIEEEER KKQYAGSNKE
     MISFINPQTG KVEESAPITK QELDEVKKFQ VLYPCYFDKN RSHKEGRRVP IEMAVENPLA
     KTISDAVREY GLLSIFEGDK CHPQDFGNPG RIRVLLKEEG KLVPSASKFS GGKRQLMKLV
     AEYLQKHPTT VESLRELPYG PDFDNIEFKK IPKVKGFKMN DIVPLHSPYL WGHPMTKSIY
     EAPKIEAPEK QFKAPKNKFK VVRR