ID   SECAB_ARATH             Reviewed;         829 AA.
AC   X5JB51; Q56W60; Q8RVQ5; Q94CK5;
DT   18-JAN-2017, integrated into UniProtKB/Swiss-Prot.
DT   11-JUN-2014, sequence version 1.
DT   03-AUG-2022, entry version 42.
DE   RecName: Full=Exocyst complex component SEC10b {ECO:0000303|PubMed:24728280};
DE            Short=AtSec10b {ECO:0000303|PubMed:24728280};
GN   Name=SEC10b {ECO:0000303|PubMed:24728280};
GN   OrderedLocusNames=At5g12365 {ECO:0000303|PubMed:24728280};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Columbia;
RA   Elias M., Cvrckova F., Zarsky V.;
RT   "Molecular characterization of the exocyst complex in Arabidopsis
RT   thaliana.";
RL   Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], TISSUE SPECIFICITY, AND DISRUPTION
RP   PHENOTYPE.
RX   PubMed=24728280; DOI=10.1371/journal.pone.0094077;
RA   Vukasinovic N., Cvrckova F., Elias M., Cole R., Fowler J.E., Zarsky V.,
RA   Synek L.;
RT   "Dissecting a hidden gene duplication: the Arabidopsis thaliana SEC10
RT   locus.";
RL   PLoS ONE 9:E94077-E94077(2014).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130714; DOI=10.1038/35048507;
RA   Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA   Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA   Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA   Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA   O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA   Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA   Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA   Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA   Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA   Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA   Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA   Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA   Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA   Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA   Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA   McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA   Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA   Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA   Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA   Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA   Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA   Bevan M., Fransz P.F.;
RT   "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL   Nature 408:823-826(2000).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [5]
RP   COMPONENT OF THE EXOCYST COMPLEX.
RX   PubMed=18492870; DOI=10.1105/tpc.108.059105;
RA   Hala M., Cole R., Synek L., Drdova E., Pecenkova T., Nordheim A.,
RA   Lamkemeyer T., Madlung J., Hochholdinger F., Fowler J.E., Zarsky V.;
RT   "An exocyst complex functions in plant cell growth in Arabidopsis and
RT   tobacco.";
RL   Plant Cell 20:1330-1345(2008).
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=19895414; DOI=10.1111/j.1469-8137.2009.03070.x;
RA   Chong Y.T., Gidda S.K., Sanford C., Parkinson J., Mullen R.T., Goring D.R.;
RT   "Characterization of the Arabidopsis thaliana exocyst complex gene families
RT   by phylogenetic, expression profiling, and subcellular localization
RT   studies.";
RL   New Phytol. 185:401-419(2010).
RN   [7]
RP   FUNCTION, AND INTERACTION WITH EXO84B.
RX   PubMed=20870962; DOI=10.1105/tpc.110.074351;
RA   Fendrych M., Synek L., Pecenkova T., Toupalova H., Cole R., Drdova E.,
RA   Nebesarova J., Sedinova M., Hala M., Fowler J.E., Zarsky V.;
RT   "The Arabidopsis exocyst complex is involved in cytokinesis and cell plate
RT   maturation.";
RL   Plant Cell 22:3053-3065(2010).
RN   [8]
RP   FUNCTION.
RX   PubMed=23163883; DOI=10.1111/tpj.12074;
RA   Drdova E.J., Synek L., Pecenkova T., Hala M., Kulich I., Fowler J.E.,
RA   Murphy A.S., Zarsky V.;
RT   "The exocyst complex contributes to PIN auxin efflux carrier recycling and
RT   polar auxin transport in Arabidopsis.";
RL   Plant J. 73:709-719(2013).
RN   [9]
RP   INTERACTION WITH EXO70E2, AND SUBCELLULAR LOCATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=24307681; DOI=10.1091/mbc.e13-10-0586;
RA   Ding Y., Wang J., Chun Lai J.H., Ling Chan V.H., Wang X., Cai Y., Tan X.,
RA   Bao Y., Xia J., Robinson D.G., Jiang L.;
RT   "Exo70E2 is essential for exocyst subunit recruitment and EXPO formation in
RT   both plants and animals.";
RL   Mol. Biol. Cell 25:412-426(2014).
CC   -!- FUNCTION: Component of the exocyst complex involved in the docking of
CC       exocytic vesicles with fusion sites on the plasma membrane during
CC       regulated or polarized secretion. Involved in polarized cell growth and
CC       organ morphogenesis. During cytokinesis, involved in cell plate
CC       initiation, cell plate maturation and formation of new primary cell
CC       wall. {ECO:0000269|PubMed:20870962, ECO:0000269|PubMed:23163883}.
CC   -!- SUBUNIT: The exocyst complex is composed of SEC3, SEC5, SEC6, SEC8,
CC       SEC10, EXO70A1 and EXO84B. Interacts with EXO84B. Binds to EXO70E2
CC       (PubMed:24307681). {ECO:0000269|PubMed:20870962,
CC       ECO:0000269|PubMed:24307681}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:24307681}.
CC       Secreted, extracellular exosome {ECO:0000269|PubMed:24307681}.
CC       Note=Shuttles from the cytoplasm to the exocyst-positive organelle
CC       (EXPO) in the presence of EXO70E2. {ECO:0000269|PubMed:24307681}.
CC   -!- TISSUE SPECIFICITY: Expressed in seedlings, roots, leaves and flowers.
CC       {ECO:0000269|PubMed:24728280}.
CC   -!- DISRUPTION PHENOTYPE: No visible phenotype, due to the redundancy with
CC       SEC10a. {ECO:0000269|PubMed:24728280}.
CC   -!- SIMILARITY: Belongs to the SEC10 family. {ECO:0000305}.
CC   -!- CAUTION: This locus, comprising the single gene At5g12370 in the
CC       original reference genome assembly, contains in fact two paralogous
CC       genes in tandem, SEC10a (At5g12370) and SEC10b (At5g12365), and a
CC       sequence segment of 7 kb in length is missing from the reference genome
CC       sequence. {ECO:0000305|PubMed:24728280}.
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DR   EMBL; AF479280; AAL87123.1; -; mRNA.
DR   EMBL; HG764169; CDJ79774.3; -; Genomic_DNA.
DR   EMBL; CP002688; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; X5JB51; -.
DR   SMR; X5JB51; -.
DR   PeptideAtlas; X5JB51; -.
DR   PRIDE; X5JB51; -.
DR   Araport; AT5G12365; -.
DR   PRO; PR:X5JB51; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; X5JB51; baseline and differential.
DR   GO; GO:0005829; C:cytosol; IDA:UniProtKB.
DR   GO; GO:0000145; C:exocyst; IDA:UniProtKB.
DR   GO; GO:0070062; C:extracellular exosome; IDA:UniProtKB.
DR   GO; GO:0016020; C:membrane; IDA:UniProtKB.
DR   GO; GO:0005886; C:plasma membrane; IDA:UniProtKB.
DR   GO; GO:0009506; C:plasmodesma; IDA:UniProtKB.
DR   GO; GO:0060321; P:acceptance of pollen; IMP:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IBA:GO_Central.
DR   GO; GO:0006893; P:Golgi to plasma membrane transport; IBA:GO_Central.
DR   InterPro; IPR009976; Sec10-like.
DR   PANTHER; PTHR12100; PTHR12100; 1.
DR   Pfam; PF07393; Sec10; 2.
PE   1: Evidence at protein level;
KW   Coiled coil; Cytoplasm; Exocytosis; Reference proteome; Secreted;
KW   Transport.
FT   CHAIN           1..829
FT                   /note="Exocyst complex component SEC10b"
FT                   /id="PRO_0000438626"
FT   COILED          244..266
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   829 AA;  90256 MW;  0CCCB0EE9CA5F536 CRC64;
     MTERIRARGP RSSSVNSVPL ILDIEDFKGD FSFDALFGNL VNDLLPSFLD EEADSGDGHG
     NIAGVDGLTN GHLRGQSAPL SSAPFFPEVD GLLSLFKDAC KELVDLRKQV DGRLNTLKKE
     VSTQDSKHRK TLTEIEKGVD GLFESFARLD GRISSVGQTA AKIGDHLQSA DAQRETASQT
     IDLIKYLMEF NGSPGDLMEL SALFSDDSRV AEAASIAQKL RSFAEEDIGR QGASTAAGNA
     TPGRGLEVAV ANLQDYCNEL ENRLLSRFDA ASQRRDLSTM SECAKILSQF NRGTSAMQHY
     VATRPMFIDV EVMNSDIRLV LGDHGSQPSP SNVARGLSAL FKEITDTVRK EAATITAVFP
     TPNEVMAILV QRVLEQRVTG ILDKILAKPS LMSPPPVQEG GLLLYLRMLA VAYERTQELA
     KDLRAVGCGD LDVEDLTESL FSSHKDEYPE HERASLKQLY QAKMEELRAE SQQVSESSGT
     IGRSKGASIS SSLQQISVTF VTEFVRWNEE AITRCTLFSS QPATLAANVK AIFTCLLDQV
     SVYITEGLER ARDSLSEAAA LRERFVLGTS VSRRVAAAAA SAAEAAAAAG ESSFKSFMVA
     VQRCGSSVAI VQQYFANSIS RLLLPVDGAH AASCEEMSTA LSKAEAAAYK GLQQCIETVM
     AEVDRLLSSE QKSTDYRSPD DGIASDHRPT NACIRVVAYL SRVLESAFTA LEGLNKQAFL
     TELGNRLEKL LLTHWQKFTF NPSGGLRLKR DLNEYVGFVK SFGAPSVDEK FELLGIIANV
     FIVAPDSLPT LFEGSPSIRK DAQRFIQLRE DYKSAKLATK LSSLWPSLS