ID   SECBL_MYCTO             Reviewed;         181 AA.
AC   Q7D7P7;
DT   29-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=SecB-like chaperone MT2006;
GN   Name=secBL; OrderedLocusNames=MT2006; ORFNames=V735_02010;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A.M., Hung D., Gomez D., Hsueh P.R., Rozo J.C., Zambrano M.M.,
RA   Desjardins C., Abeel T., Young S., Zeng Q., Gargeya S., Abouelleil A.,
RA   Alvarado L., Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., Murphy C.,
RA   Naylor J., Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T.,
RA   Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The genome sequence of Mycobacterium tuberculosis CDC1551.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Chaperone component of an atypical, type II toxin-antitoxin
CC       chaperone (TAC) module, probably required for antitoxin HigA1 to
CC       neutralize its cognate toxin HigB1. {ECO:0000250|UniProtKB:P95257}.
CC   -!- SUBUNIT: Homotetramer, interacts with antitoxin HigA1.
CC       {ECO:0000250|UniProtKB:P95257}.
CC   -!- INDUCTION: Operon autorepressed by HigA1.
CC       {ECO:0000250|UniProtKB:P95257}.
CC   -!- SIMILARITY: Belongs to the SecB-like family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK46278.1; -; Genomic_DNA.
DR   EMBL; JLBH01000002; KBN13170.1; -; Genomic_DNA.
DR   RefSeq; WP_003899098.1; NZ_KK341227.1.
DR   AlphaFoldDB; Q7D7P7; -.
DR   SMR; Q7D7P7; -.
DR   EnsemblBacteria; AAK46278; AAK46278; MT2006.
DR   KEGG; mtc:MT2006; -.
DR   PATRIC; fig|83331.31.peg.2162; -.
DR   HOGENOM; CLU_1632606_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   Gene3D; 3.10.420.10; -; 1.
DR   InterPro; IPR035958; SecB-like_sf.
DR   SUPFAM; SSF54611; SSF54611; 1.
PE   3: Inferred from homology;
KW   Chaperone.
FT   CHAIN           1..181
FT                   /note="SecB-like chaperone MT2006"
FT                   /id="PRO_0000432915"
SQ   SEQUENCE   181 AA;  20105 MW;  C3613E7A28446A40 CRC64;
     MTDRTDADDL DLQRVGARLA ARAQIRDIRL LRTQAAVHRA PKPAQGLTYD LEFEPAVDAD
     PATISAFVVR ISCHLRIQNQ AADNDVKEGD TKDETQDVAT ADFEFAALFD YHLQEGEDDP
     TEEELTAYAA TTGRFALYPY IREYVYDLTG RLALPPLTLE ILSRPMPVSP GAQWPATRGT
     P