ID   SECB_SERMA              Reviewed;         156 AA.
AC   Q8KRM2;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Protein-export protein SecB;
GN   Name=secB;
OS   Serratia marcescens.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Serratia.
OX   NCBI_TaxID=615;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RX   PubMed=12486043; DOI=10.1128/jb.185.1.80-88.2003;
RA   Sapriel G., Wandersman C., Delepelaire P.;
RT   "The SecB chaperone is bifunctional in Serratia marcescens: SecB is
RT   involved in the Sec pathway and required for HasA secretion by the ABC
RT   transporter.";
RL   J. Bacteriol. 185:80-88(2003).
CC   -!- FUNCTION: One of the proteins required for the normal export of
CC       preproteins out of the cell cytoplasm. It is a molecular chaperone that
CC       binds to a subset of precursor proteins, maintaining them in a
CC       translocation-competent state. It specifically binds to its receptor
CC       SecA. Also required for the secretion of HasA via an ABC transporter
CC       system. {ECO:0000269|PubMed:12486043}.
CC   -!- SUBUNIT: Homotetramer, a dimer of dimers. One homotetramer interacts
CC       with 1 SecA dimer (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SecB family. {ECO:0000305}.
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DR   EMBL; AF528189; AAM89273.1; -; Genomic_DNA.
DR   RefSeq; WP_004931139.1; NZ_WUWF01000031.1.
DR   AlphaFoldDB; Q8KRM2; -.
DR   SMR; Q8KRM2; -.
DR   STRING; 273526.SMDB11_4041; -.
DR   GeneID; 64305968; -.
DR   GeneID; 66717103; -.
DR   OrthoDB; 1624074at2; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051262; P:protein tetramerization; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.10.420.10; -; 1.
DR   HAMAP; MF_00821; SecB; 1.
DR   InterPro; IPR003708; SecB.
DR   InterPro; IPR035958; SecB-like_sf.
DR   PANTHER; PTHR36918; PTHR36918; 1.
DR   Pfam; PF02556; SecB; 1.
DR   PRINTS; PR01594; SECBCHAPRONE.
DR   SUPFAM; SSF54611; SSF54611; 1.
DR   TIGRFAMs; TIGR00809; secB; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Protein transport; Translocation; Transport.
FT   CHAIN           1..156
FT                   /note="Protein-export protein SecB"
FT                   /id="PRO_0000055416"
SQ   SEQUENCE   156 AA;  17226 MW;  6345A0173FA39441 CRC64;
     MSEQNSTEMA FQIQRIYTKD ISFEAPNAPQ VFQQEWQPEV KLDLDTASSQ LADEVYEVVL
     RVTVTATLGE ETAFLCEVQQ AGIFSVAGIE GTQLAHCLGA YCPNILFPYA RECITSLVSR
     GTFPQLNLAP VNFDALFMNY LQQQAEGEGA APHQDA