ID   SECD_ANATU              Reviewed;         464 AA.
AC   E8N5I8;
DT   21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-APR-2011, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Protein translocase subunit SecD {ECO:0000255|HAMAP-Rule:MF_01463};
GN   Name=secD {ECO:0000255|HAMAP-Rule:MF_01463}; OrderedLocusNames=ANT_16760;
OS   Anaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 /
OS   UNI-1).
OC   Bacteria; Chloroflexi; Anaerolineae; Anaerolineales; Anaerolineaceae;
OC   Anaerolinea.
OX   NCBI_TaxID=926569;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1;
RA   Narita-Yamada S., Kishi E., Watanabe Y., Takasaki K., Ankai A., Oguchi A.,
RA   Fukui S., Takahashi M., Yashiro I., Hosoyama A., Sekiguchi Y., Hanada S.,
RA   Fujita N.;
RT   "Whole genome sequence of Anaerolinea thermophila UNI-1.";
RL   Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the Sec protein translocase complex. Interacts with
CC       the SecYEG preprotein conducting channel. SecDF uses the proton motive
CC       force (PMF) to complete protein translocation after the ATP-dependent
CC       function of SecA. {ECO:0000255|HAMAP-Rule:MF_01463}.
CC   -!- SUBUNIT: Forms a complex with SecF. Part of the essential Sec protein
CC       translocation apparatus which comprises SecA, SecYEG and auxiliary
CC       proteins SecDF. Other proteins may also be involved.
CC       {ECO:0000255|HAMAP-Rule:MF_01463}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01463};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01463}.
CC   -!- SIMILARITY: Belongs to the SecD/SecF family. SecD subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01463}.
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DR   EMBL; AP012029; BAJ63702.1; -; Genomic_DNA.
DR   RefSeq; WP_013560081.1; NC_014960.1.
DR   AlphaFoldDB; E8N5I8; -.
DR   SMR; E8N5I8; -.
DR   STRING; 926569.ANT_16760; -.
DR   EnsemblBacteria; BAJ63702; BAJ63702; ANT_16760.
DR   KEGG; atm:ANT_16760; -.
DR   eggNOG; COG0342; Bacteria.
DR   HOGENOM; CLU_007894_4_2_0; -.
DR   OMA; MVVYYRL; -.
DR   OrthoDB; 121331at2; -.
DR   Proteomes; UP000008922; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015450; F:protein-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR   GO; GO:0043952; P:protein transport by the Sec complex; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01463_B; SecD_B; 1.
DR   InterPro; IPR005791; SecD.
DR   InterPro; IPR022813; SecD/SecF_arch_bac.
DR   InterPro; IPR022645; SecD/SecF_bac.
DR   PANTHER; PTHR30081; PTHR30081; 1.
DR   Pfam; PF02355; SecD_SecF; 1.
DR   TIGRFAMs; TIGR00916; 2A0604s01; 1.
DR   TIGRFAMs; TIGR01129; secD; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Protein transport; Reference proteome;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..464
FT                   /note="Protein translocase subunit SecD"
FT                   /id="PRO_0000412672"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        293..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        322..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        343..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        396..416
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        419..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   REGION          144..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   464 AA;  50867 MW;  76142F2EFF507BD8 CRC64;
     MKRYYFTLAL IVLLLGLTIW FNVPGHPQIK IGNFERSMDL IQGLDLQGGV QVLLEADLPA
     ETPIDPQALE DARTILENRT NALGVSENLF QVAGERRIVA EFPGLSDPEK VLAVIKETGL
     LEFVDLQDNP ENLQEGNLIL TDFGQTSTST QPTETTTAPA TEGQESLAST TVYHTIMTGK
     DLKSVVVSRN PNTGEVVIDF TLSDEGAKIF DEYTSNNIGK ILAIVLDKKI ISAPRVQGRI
     PSGQGQITGN FTLETANNLA IQMRYGALPI PFKVVESRVI GPTLGRDSLQ KSLLAGYIGF
     TIVILFMGIY YRLPGVMADL SLIVYALITL TLFRFIPVTL TLPGIAGFLL STGSALDANI
     LIFERLKEEL RAGRTFSQAL DLAWKRALPS IRDSNIATLI TVVILFIFGS QFGATIVKGF
     AFTLGVGIFV SLFCAMVVTR TFMYILVDRM KPQAKHLKWF GILD