ID   SECD_BORBU              Reviewed;         586 AA.
AC   O51596;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   30-APR-2003, sequence version 2.
DT   25-MAY-2022, entry version 122.
DE   RecName: Full=Protein translocase subunit SecD {ECO:0000255|HAMAP-Rule:MF_01463};
GN   Name=secD {ECO:0000255|HAMAP-Rule:MF_01463}; OrderedLocusNames=BB_0652;
OS   Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)
OS   (Borrelia burgdorferi).
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=224326;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35210 / DSM 4680 / CIP 102532 / B31;
RX   PubMed=9403685; DOI=10.1038/37551;
RA   Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A.,
RA   Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L.,
RA   Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L.,
RA   Peterson J.D., Kerlavage A.R., Quackenbush J., Salzberg S.L., Hanson M.,
RA   van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F.,
RA   Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C.,
RA   Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B.,
RA   Smith H.O., Venter J.C.;
RT   "Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi.";
RL   Nature 390:580-586(1997).
CC   -!- FUNCTION: Part of the Sec protein translocase complex. Interacts with
CC       the SecYEG preprotein conducting channel. SecDF uses the proton motive
CC       force (PMF) to complete protein translocation after the ATP-dependent
CC       function of SecA. {ECO:0000255|HAMAP-Rule:MF_01463}.
CC   -!- SUBUNIT: Forms a complex with SecF. Part of the essential Sec protein
CC       translocation apparatus which comprises SecA, SecYEG and auxiliary
CC       proteins SecDF. Other proteins may also be involved.
CC       {ECO:0000255|HAMAP-Rule:MF_01463}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01463}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01463}.
CC   -!- SIMILARITY: Belongs to the SecD/SecF family. SecD subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01463}.
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DR   EMBL; AE000783; AAC66993.2; -; Genomic_DNA.
DR   RefSeq; NP_212786.1; NC_001318.1.
DR   RefSeq; WP_010889789.1; NC_001318.1.
DR   STRING; 224326.BB_0652; -.
DR   PRIDE; O51596; -.
DR   EnsemblBacteria; AAC66993; AAC66993; BB_0652.
DR   KEGG; bbu:BB_0652; -.
DR   PATRIC; fig|224326.49.peg.1043; -.
DR   HOGENOM; CLU_007894_4_3_12; -.
DR   OMA; MVVYYRL; -.
DR   Proteomes; UP000001807; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015450; F:protein-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR   GO; GO:0043952; P:protein transport by the Sec complex; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01463_B; SecD_B; 1.
DR   InterPro; IPR001036; Acrflvin-R.
DR   InterPro; IPR005791; SecD.
DR   InterPro; IPR022813; SecD/SecF_arch_bac.
DR   InterPro; IPR022645; SecD/SecF_bac.
DR   PANTHER; PTHR30081; PTHR30081; 1.
DR   Pfam; PF02355; SecD_SecF; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   TIGRFAMs; TIGR00916; 2A0604s01; 1.
DR   TIGRFAMs; TIGR01129; secD; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Reference proteome; Translocation; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..586
FT                   /note="Protein translocase subunit SecD"
FT                   /id="PRO_0000095957"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        418..438
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        439..459
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        465..485
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        521..541
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        546..566
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
SQ   SEQUENCE   586 AA;  65028 MW;  4707A9C71AD15B42 CRC64;
     MKKGSKLILI LLVTFFACLL IFPTLKWYFL MSVEDKKISS YSQEALRDYS KKKALNDLVK
     LKELYNKDPN SSIPASLSYL IPIAKNNYRS SMKIPPNIFT AKTLREGFLT DSDMGEVSLE
     IYRYYENIKK GKSRIIHLGL DLSGGMSVTI SLDYSSVEKK LGRSLTFAER EDAIYRIMQI
     LKDRVBRFGL TEPKIVREAG GNKIFLDIPG EKDESRVSTL LSGKGNLTFY VVDDESTSLL
     HRKILEAGSL FSIPEIQASM NLPDSKQIFP WYVKDSYGVD DESSVRYYVV DASPENSFDG
     AHIKDAGVSN DPRTGRDTVA FSLDVDGSEK FFKFTQKNVG KSLAVVMEGK IKSVAGIGYA
     ITGGNVSIQG DSFDKKEAQD LALVFKTAAF PVDIKIDDLR IIGPTLGART IDLGIKASAL
     ALCLVFLFIC VYYGLSGVVA GFSLVIYNVF LILAILSAFN FTLTLTSIAG LILTMGMAVD
     INIVIYERIK EEIREGRRFE NAFEAGFKKA FLSIMDANIT TFIAVLFLTL LGTGVIQGFA
     WSLSVGIVAS LFSSLIFSRF ILEFIISVRK SKFISISWSS KYAKSN