ID   SECD_METJA              Reviewed;         396 AA.
AC   Q57575;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=Protein-export membrane protein SecD {ECO:0000255|HAMAP-Rule:MF_01463};
GN   Name=secD {ECO:0000255|HAMAP-Rule:MF_01463}; OrderedLocusNames=MJ0111;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- FUNCTION: Involved in protein export. {ECO:0000255|HAMAP-
CC       Rule:MF_01463}.
CC   -!- SUBUNIT: Part of the protein translocation apparatus. Forms a complex
CC       with SecF. {ECO:0000255|HAMAP-Rule:MF_01463}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01463};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01463}.
CC   -!- SIMILARITY: Belongs to the SecD/SecF family. SecD subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01463}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L77117; AAB98092.1; -; Genomic_DNA.
DR   PIR; G64313; G64313.
DR   RefSeq; WP_010869603.1; NC_000909.1.
DR   AlphaFoldDB; Q57575; -.
DR   SMR; Q57575; -.
DR   STRING; 243232.MJ_0111; -.
DR   EnsemblBacteria; AAB98092; AAB98092; MJ_0111.
DR   GeneID; 1450952; -.
DR   KEGG; mja:MJ_0111; -.
DR   eggNOG; arCOG03055; Archaea.
DR   HOGENOM; CLU_007894_5_1_2; -.
DR   InParanoid; Q57575; -.
DR   OMA; SAHLQMM; -.
DR   OrthoDB; 14000at2157; -.
DR   PhylomeDB; Q57575; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01463_A; SecD_A; 1.
DR   InterPro; IPR022813; SecD/SecF_arch_bac.
DR   InterPro; IPR022646; SecD/SecF_CS.
DR   InterPro; IPR024912; SecD_arc.
DR   PANTHER; PTHR30081; PTHR30081; 1.
DR   Pfam; PF07549; Sec_GG; 1.
DR   Pfam; PF02355; SecD_SecF; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Protein transport; Reference proteome;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..396
FT                   /note="Protein-export membrane protein SecD"
FT                   /id="PRO_0000095990"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        243..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        272..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        298..318
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        338..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        360..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
SQ   SEQUENCE   396 AA;  43052 MW;  70BA0A62C74E9251 CRC64;
     MDISKLLKDR KILILIIFVT LSVFLIVFKG LDFGIDLSGG TIIVLKAEKP MSDKEIEATI
     KIITERLNYN GLNDVVIYPR GNDEIIVEIP KSCDTDRIIK ILKQQGVFVA KIDNITAYTG
     SDVQNVELPT KIPQGETWAY GVPFELTLEG AKKFAEVAKG KAYHKVELYM DGKLISAPVL
     SPDLADGKPH PQQVITVGAY PPTKEEIDEA MAIYSALKSG ALPVKLDIEY ISTISPEFGK
     EFLKGTAIAL LLAFIAVGII VSIRYKQPKI AIPILITCIS EVIIILGFAS LIDWKLDLPS
     IAGIIAAVGT GVDNQIVITD EALKRGAGKI RASIKRAFFI IFASAATSIA AMLPLFVLGV
     GMLKGFAITT IAGVLIGIFI TRPAFARIIE EMFKKF