ID   SECD_RICPR              Reviewed;         518 AA.
AC   Q9ZCW8;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=Protein translocase subunit SecD {ECO:0000255|HAMAP-Rule:MF_01463};
GN   Name=secD {ECO:0000255|HAMAP-Rule:MF_01463}; OrderedLocusNames=RP586;
OS   Rickettsia prowazekii (strain Madrid E).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=272947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Madrid E;
RX   PubMed=9823893; DOI=10.1038/24094;
RA   Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T.,
RA   Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H.,
RA   Kurland C.G.;
RT   "The genome sequence of Rickettsia prowazekii and the origin of
RT   mitochondria.";
RL   Nature 396:133-140(1998).
CC   -!- FUNCTION: Part of the Sec protein translocase complex. Interacts with
CC       the SecYEG preprotein conducting channel. SecDF uses the proton motive
CC       force (PMF) to complete protein translocation after the ATP-dependent
CC       function of SecA. {ECO:0000255|HAMAP-Rule:MF_01463}.
CC   -!- SUBUNIT: Forms a complex with SecF. Part of the essential Sec protein
CC       translocation apparatus which comprises SecA, SecYEG and auxiliary
CC       proteins SecDF-YajC and YidC. {ECO:0000255|HAMAP-Rule:MF_01463}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01463}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01463}.
CC   -!- SIMILARITY: Belongs to the SecD/SecF family. SecD subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01463}.
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DR   EMBL; AJ235272; CAA15031.1; -; Genomic_DNA.
DR   PIR; E71663; E71663.
DR   RefSeq; NP_220955.1; NC_000963.1.
DR   RefSeq; WP_004597905.1; NC_000963.1.
DR   AlphaFoldDB; Q9ZCW8; -.
DR   SMR; Q9ZCW8; -.
DR   STRING; 272947.RP586; -.
DR   EnsemblBacteria; CAA15031; CAA15031; CAA15031.
DR   GeneID; 57569712; -.
DR   KEGG; rpr:RP586; -.
DR   PATRIC; fig|272947.5.peg.602; -.
DR   eggNOG; COG0342; Bacteria.
DR   HOGENOM; CLU_007894_4_3_5; -.
DR   OMA; MVVYYRL; -.
DR   Proteomes; UP000002480; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015450; F:protein-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR   GO; GO:0043952; P:protein transport by the Sec complex; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01463_B; SecD_B; 1.
DR   InterPro; IPR005791; SecD.
DR   InterPro; IPR022813; SecD/SecF_arch_bac.
DR   InterPro; IPR022645; SecD/SecF_bac.
DR   PANTHER; PTHR30081; PTHR30081; 1.
DR   Pfam; PF02355; SecD_SecF; 1.
DR   TIGRFAMs; TIGR00916; 2A0604s01; 1.
DR   TIGRFAMs; TIGR01129; secD; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Reference proteome; Translocation; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..518
FT                   /note="Protein translocase subunit SecD"
FT                   /id="PRO_0000095968"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        356..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        377..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        406..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        463..483
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
FT   TRANSMEM        486..506
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01463"
SQ   SEQUENCE   518 AA;  56712 MW;  86D6FC2A5B5DE2AA CRC64;
     MQNLPKWKIV LSIICTVFAI ICALPNFIQI NSKFLPHDSI NLGLDLRGGA NLLLDVDFDT
     YLNDSMENLA DTLRKNLRKH KIGYKNLLVR HNNIQLEVRS PEVLKSLKKI INKIDPEIII
     GVNKNKIKLR YSESRFNDLL NKVVEQSIEI VRMRVDSTGT KEPTLQRQGN KHILLQVPGS
     ENPSYLKNIL GKTAKLTFHL VDENANIEDA IKGHVPLGSM LIKGDSKHHG EYYIVIKKKV
     LLSGAHLTKA SASFDQNSQP IVAFSFNNLG SKIFGEITKN NTGKRLAIVL DNKLLSAPII
     NGAIIGGNGI ITGNFTIESA NELALLLRVG SLPTPLKIIE ERSIGPNLGA DSIESGKKAG
     LIGFVAVCIF MILSYGVIGL FANIALILAL LYILALLSLF QATLTLPGIA GIILTIGMAV
     DANVLIYERI KEELHKGVSN LYAIRTGFES AFATIIDSNI TTLIVAFALY IFGVGAIKGF
     AVALTIGIIS SMFSAIIITK LLIDVWVKYF KPKKLGLL