SECE_STACT
ID SECE_STACT Reviewed; 65 AA.
AC P36253; B9DKW8;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Protein translocase subunit SecE {ECO:0000255|HAMAP-Rule:MF_00422};
GN Name=secE {ECO:0000255|HAMAP-Rule:MF_00422}; OrderedLocusNames=Sca_0191;
OS Staphylococcus carnosus (strain TM300).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=396513;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8181706; DOI=10.1111/j.1574-6968.1994.tb06751.x;
RA Meens J., Klose M., Freudl R.;
RT "The Staphylococcus carnosus secE gene: cloning, nucleotide sequence, and
RT functional characterization in Escherichia coli secE mutant strains.";
RL FEMS Microbiol. Lett. 117:113-119(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TM300;
RX PubMed=19060169; DOI=10.1128/aem.01982-08;
RA Rosenstein R., Nerz C., Biswas L., Resch A., Raddatz G., Schuster S.C.,
RA Goetz F.;
RT "Genome analysis of the meat starter culture bacterium Staphylococcus
RT carnosus TM300.";
RL Appl. Environ. Microbiol. 75:811-822(2009).
CC -!- FUNCTION: Essential subunit of the Sec protein translocation channel
CC SecYEG. Clamps together the 2 halves of SecY. May contact the channel
CC plug during translocation. {ECO:0000255|HAMAP-Rule:MF_00422}.
CC -!- SUBUNIT: Component of the Sec protein translocase complex. Heterotrimer
CC consisting of SecY, SecE and SecG subunits. The heterotrimers can form
CC oligomers, although 1 heterotrimer is thought to be able to translocate
CC proteins. Interacts with the ribosome. Interacts with SecDF, and other
CC proteins may be involved. Interacts with SecA. {ECO:0000255|HAMAP-
CC Rule:MF_00422}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00422};
CC Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00422}.
CC -!- SIMILARITY: Belongs to the SecE/SEC61-gamma family. {ECO:0000255|HAMAP-
CC Rule:MF_00422}.
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DR EMBL; X76134; CAA53737.1; -; Genomic_DNA.
DR EMBL; AM295250; CAL27104.1; -; Genomic_DNA.
DR PIR; S38869; S38869.
DR RefSeq; WP_012664219.1; NC_012121.1.
DR AlphaFoldDB; P36253; -.
DR SMR; P36253; -.
DR STRING; 396513.SCA_0191; -.
DR GeneID; 60546112; -.
DR KEGG; sca:SCA_0191; -.
DR eggNOG; COG0690; Bacteria.
DR HOGENOM; CLU_113663_8_2_9; -.
DR OMA; EMKRVSW; -.
DR OrthoDB; 1974284at2; -.
DR BioCyc; SCAR396513:SCA_RS00990-MON; -.
DR Proteomes; UP000000444; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008320; F:protein transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:UniProtKB-UniRule.
DR GO; GO:0009306; P:protein secretion; IEA:UniProtKB-UniRule.
DR GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR GO; GO:0043952; P:protein transport by the Sec complex; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.5.1030; -; 1.
DR HAMAP; MF_00422; SecE; 1.
DR InterPro; IPR005807; SecE_bac.
DR InterPro; IPR038379; SecE_sf.
DR InterPro; IPR001901; Translocase_SecE/Sec61-g.
DR PANTHER; PTHR33910; PTHR33910; 1.
DR Pfam; PF00584; SecE; 1.
DR TIGRFAMs; TIGR00964; secE_bact; 1.
DR PROSITE; PS01067; SECE_SEC61G; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Protein transport; Translocation; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..65
FT /note="Protein translocase subunit SecE"
FT /id="PRO_0000104180"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00422"
SQ SEQUENCE 65 AA; 7462 MW; 083BEB355B3AAFCA CRC64;
MAEDKKKAPK DSFFKGVISE MEKTSWPTKE EILKYTTIVI VTVVFFLIFF YALDLGIGKL
IELIS
