ID   SECE_STRVG              Reviewed;          93 AA.
AC   P36691;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 2.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Protein translocase subunit SecE {ECO:0000255|HAMAP-Rule:MF_00422};
GN   Name=secE {ECO:0000255|HAMAP-Rule:MF_00422};
OS   Streptomyces virginiae.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces virginiae group.
OX   NCBI_TaxID=1961;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8675024; DOI=10.1016/0378-1119(96)00067-4;
RA   Katayama M., Sakai Y., Okamoto S., Ihara F., Nihira T., Yamada Y.;
RT   "Gene organization in the ada-rplL region of Streptomyces virginiae.";
RL   Gene 171:135-136(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=MAFF10-06014;
RX   PubMed=1309760; DOI=10.1016/s0021-9258(18)48400-1;
RA   Okamoto S., Nihirra T., Kataoka H., Suzuki A., Yamada Y.;
RT   "Purification and molecular cloning of a butyrolactone autoregulator
RT   receptor from Streptomyces virginiae.";
RL   J. Biol. Chem. 267:1093-1098(1992).
CC   -!- FUNCTION: Essential subunit of the Sec protein translocation channel
CC       SecYEG. Clamps together the 2 halves of SecY. May contact the channel
CC       plug during translocation. {ECO:0000255|HAMAP-Rule:MF_00422}.
CC   -!- SUBUNIT: Component of the Sec protein translocase complex. Heterotrimer
CC       consisting of SecY, SecE and SecG subunits. The heterotrimers can form
CC       oligomers, although 1 heterotrimer is thought to be able to translocate
CC       proteins. Interacts with the ribosome. Interacts with SecDF, and other
CC       proteins may be involved. Interacts with SecA. {ECO:0000255|HAMAP-
CC       Rule:MF_00422}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00422};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00422}.
CC   -!- SIMILARITY: Belongs to the SecE/SEC61-gamma family. {ECO:0000255|HAMAP-
CC       Rule:MF_00422}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA09300.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; D50624; BAA09300.1; ALT_INIT; Genomic_DNA.
DR   EMBL; D10468; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; WP_030388883.1; NZ_LGUV01000155.1.
DR   AlphaFoldDB; P36691; -.
DR   SMR; P36691; -.
DR   STRING; 1961.JOAK01000021_gene7140; -.
DR   eggNOG; COG0690; Bacteria.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0009306; P:protein secretion; IEA:UniProtKB-UniRule.
DR   GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR   GO; GO:0043952; P:protein transport by the Sec complex; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.5.1030; -; 1.
DR   HAMAP; MF_00422; SecE; 1.
DR   InterPro; IPR005807; SecE_bac.
DR   InterPro; IPR038379; SecE_sf.
DR   InterPro; IPR001901; Translocase_SecE/Sec61-g.
DR   PANTHER; PTHR33910; PTHR33910; 1.
DR   Pfam; PF00584; SecE; 1.
DR   TIGRFAMs; TIGR00964; secE_bact; 1.
DR   PROSITE; PS01067; SECE_SEC61G; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Protein transport; Translocation; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..93
FT                   /note="Protein translocase subunit SecE"
FT                   /id="PRO_0000104187"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00422"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        49
FT                   /note="R -> P (in Ref. 2; D10468)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        65
FT                   /note="V -> L (in Ref. 2; D10468)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        75
FT                   /note="G -> R (in Ref. 2; D10468)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   93 AA;  10447 MW;  63000CD09CE67B83 CRC64;
     MTDALGSIDM PDAEDETREK KARKGGKRGK KGPLGRLALF YRQIVAELRK VVWPTRNQLT
     TYTTVVIVFV VIMIGLVTVI DFGFEKAIKF VFG