SECF_THEGJ
ID SECF_THEGJ Reviewed; 315 AA.
AC C5A3H3;
DT 21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 64.
DE RecName: Full=Protein-export membrane protein SecF {ECO:0000255|HAMAP-Rule:MF_01464};
GN Name=secF {ECO:0000255|HAMAP-Rule:MF_01464}; OrderedLocusNames=TGAM_0283;
OS Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=593117;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15229 / JCM 11827 / EJ3;
RX PubMed=19558674; DOI=10.1186/gb-2009-10-6-r70;
RA Zivanovic Y., Armengaud J., Lagorce A., Leplat C., Guerin P., Dutertre M.,
RA Anthouard V., Forterre P., Wincker P., Confalonieri F.;
RT "Genome analysis and genome-wide proteomics of Thermococcus gammatolerans,
RT the most radioresistant organism known amongst the Archaea.";
RL Genome Biol. 10:R70.1-R70.23(2007).
CC -!- FUNCTION: Involved in protein export. {ECO:0000255|HAMAP-
CC Rule:MF_01464}.
CC -!- SUBUNIT: Part of the protein translocation apparatus. Forms a complex
CC with SecD. {ECO:0000255|HAMAP-Rule:MF_01464}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01464};
CC Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01464}.
CC -!- SIMILARITY: Belongs to the SecD/SecF family. SecF subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01464}.
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DR EMBL; CP001398; ACS32785.1; -; Genomic_DNA.
DR RefSeq; WP_015857904.1; NC_012804.1.
DR AlphaFoldDB; C5A3H3; -.
DR SMR; C5A3H3; -.
DR STRING; 593117.TGAM_0283; -.
DR PaxDb; C5A3H3; -.
DR EnsemblBacteria; ACS32785; ACS32785; TGAM_0283.
DR GeneID; 7988939; -.
DR KEGG; tga:TGAM_0283; -.
DR PATRIC; fig|593117.10.peg.286; -.
DR eggNOG; arCOG03054; Archaea.
DR HOGENOM; CLU_060478_0_0_2; -.
DR OMA; DLMNTYL; -.
DR OrthoDB; 63405at2157; -.
DR Proteomes; UP000001488; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:UniProtKB-UniRule.
DR GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01464_A; SecF_A; 1.
DR InterPro; IPR022813; SecD/SecF_arch_bac.
DR InterPro; IPR024921; SecF_arc.
DR PANTHER; PTHR30081; PTHR30081; 1.
DR Pfam; PF02355; SecD_SecF; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Protein transport; Translocation; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..315
FT /note="Protein-export membrane protein SecF"
FT /id="PRO_0000412712"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01464"
FT TRANSMEM 152..172
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01464"
FT TRANSMEM 181..201
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01464"
FT TRANSMEM 205..225
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01464"
FT TRANSMEM 242..264
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01464"
FT TRANSMEM 282..302
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01464"
SQ SEQUENCE 315 AA; 34762 MW; 8F9EF3B9B1530938 CRC64;
MGTKKQKTKK KPSDEILETK RKRLSFLVRM EPRKMVLYPL VVFLVAALIL AVHFPEKGID
LKGGVVVTVY HVSASPDELA SYVKEKTGID VRAEEFKDPI TGLSGIRIYA PAKTAPSKIA
DEISNAIRLK YKDADVTPRV VDPTFGKIAQ KQGIKAVIYA FIGMAIVVFL FFRDPVPSGT
IIFSAFSDMV IALATMGILG IELTTATIAA LLMLIGYTVD SNILLTTRLL RRKEDTIEDA
YLSAVSTGFT MSTTTLGALF ILWLVSTSEV IDSITIVLIF GLLADFMNTW IFNAGVLRWY
IASPLKFSIK LRRGK
