ID   SECG_ECO57              Reviewed;         110 AA.
AC   P0AGA1; P33582;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Protein-export membrane protein SecG;
DE   AltName: Full=P12;
DE   AltName: Full=Preprotein translocase band 1 subunit;
GN   Name=secG; OrderedLocusNames=Z4537, ECs4054;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Involved in protein export. Participates in an early event of
CC       protein translocation (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- PTM: The N-terminus is blocked. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SecG family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG58309.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB37477.1; -; Genomic_DNA.
DR   PIR; F91135; F91135.
DR   RefSeq; NP_312081.1; NC_002695.1.
DR   RefSeq; WP_001295556.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0AGA1; -.
DR   SMR; P0AGA1; -.
DR   STRING; 155864.EDL933_4403; -.
DR   EnsemblBacteria; AAG58309; AAG58309; Z4537.
DR   EnsemblBacteria; BAB37477; BAB37477; ECs_4054.
DR   GeneID; 60901971; -.
DR   GeneID; 916105; -.
DR   KEGG; ece:Z4537; -.
DR   KEGG; ecs:ECs_4054; -.
DR   PATRIC; fig|386585.9.peg.4233; -.
DR   eggNOG; COG1314; Bacteria.
DR   HOGENOM; CLU_094156_2_2_6; -.
DR   OMA; MYEVLMV; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015450; F:protein-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   InterPro; IPR004692; SecG.
DR   PANTHER; PTHR34182; PTHR34182; 1.
DR   Pfam; PF03840; SecG; 1.
DR   PRINTS; PR01651; SECGEXPORT.
DR   TIGRFAMs; TIGR00810; secG; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Reference proteome; Translocation; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..110
FT                   /note="Protein-export membrane protein SecG"
FT                   /id="PRO_0000157226"
FT   TOPO_DOM        1..3
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        4..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        23..54
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        55..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        73..110
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          81..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   110 AA;  11365 MW;  8DC7663F94D32F2F CRC64;
     MYEALLVVFL IVAIGLVGLI MLQQGKGADM GASFGAGASA TLFGSSGSGN FMTRMTALLA
     TLFFIISLVL GNINSNKTNK GSEWENLSAP AKTEQTQPAA PAKPTSDIPN