ID   SECG_HELPY              Reviewed;         199 AA.
AC   O25847;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 2.
DT   25-MAY-2022, entry version 116.
DE   RecName: Full=Protein-export membrane protein SecG;
GN   Name=secG; OrderedLocusNames=HP_1255;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
CC   -!- FUNCTION: Involved in protein export. Participates in an early event of
CC       protein translocation (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SecG family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD08301.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE000511; AAD08301.1; ALT_INIT; Genomic_DNA.
DR   PIR; G64676; G64676.
DR   RefSeq; NP_208047.1; NC_000915.1.
DR   RefSeq; WP_001862740.1; NC_000915.1.
DR   AlphaFoldDB; O25847; -.
DR   DIP; DIP-3688N; -.
DR   IntAct; O25847; 8.
DR   MINT; O25847; -.
DR   STRING; 85962.C694_06485; -.
DR   PaxDb; O25847; -.
DR   DNASU; 898868; -.
DR   EnsemblBacteria; AAD08301; AAD08301; HP_1255.
DR   KEGG; hpy:HP_1255; -.
DR   PATRIC; fig|85962.47.peg.1347; -.
DR   eggNOG; COG1314; Bacteria.
DR   OMA; MAKLTMF; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0015450; F:protein-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IBA:GO_Central.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   GO; GO:0043952; P:protein transport by the Sec complex; IBA:GO_Central.
DR   InterPro; IPR004692; SecG.
DR   PANTHER; PTHR34182; PTHR34182; 1.
DR   Pfam; PF03840; SecG; 1.
DR   PRINTS; PR01651; SECGEXPORT.
DR   TIGRFAMs; TIGR00810; secG; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Protein transport; Reference proteome;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..199
FT                   /note="Protein-export membrane protein SecG"
FT                   /id="PRO_0000157229"
FT   TRANSMEM        2..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          92..199
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..134
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        145..175
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        176..190
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   199 AA;  21460 MW;  7E69B539B2F9B8EC CRC64;
     MTSALLGLQI VLAVLIVVVV LLQKSSSIGL GAYSGSNESL FGAKGPASFM AKLTMFLGLL
     FVINTIALGY FYNKEYGKSV LDETKTNKEL SPLVPATGTL NPALNPTLNP TLNPLEQAPT
     NPLMPQQTPN ELPKEPAKTP SVESPKQNEK NEKNDAKENG IKGVEKTKEN AKTPPTTHQK
     PKTHATQTNA HTNQKKDEK