SECG_MYCBO
ID SECG_MYCBO Reviewed; 77 AA.
AC P66792; A0A1R3XYD9; O06819; X2BI51;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 25-MAY-2022, entry version 93.
DE RecName: Full=Probable protein-export membrane protein SecG;
GN Name=secG; OrderedLocusNames=BQ2027_MB1475;
OS Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=233413;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT "The complete genome sequence of Mycobacterium bovis.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA Robbe-Austerman S., Gordon S.V.;
RT "Updated reference genome sequence and annotation of Mycobacterium bovis
RT AF2122/97.";
RL Genome Announc. 5:E00157-E00157(2017).
CC -!- FUNCTION: Involved in protein export. Participates in an early event of
CC protein translocation (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the SecG family. {ECO:0000305}.
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DR EMBL; LT708304; SIU00078.1; -; Genomic_DNA.
DR RefSeq; NP_855127.1; NC_002945.3.
DR RefSeq; WP_003407407.1; NC_002945.4.
DR AlphaFoldDB; P66792; -.
DR EnsemblBacteria; SIU00078; SIU00078; BQ2027_MB1475.
DR GeneID; 45425418; -.
DR PATRIC; fig|233413.5.peg.1611; -.
DR OMA; WFACIVV; -.
DR Proteomes; UP000001419; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015450; F:protein-transporting ATPase activity; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR InterPro; IPR004692; SecG.
DR Pfam; PF03840; SecG; 1.
DR TIGRFAMs; TIGR00810; secG; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Protein transport; Translocation; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..77
FT /note="Probable protein-export membrane protein SecG"
FT /id="PRO_0000157233"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 77 AA; 8163 MW; 6DB2403163699EC6 CRC64;
MELALQITLI VTSVLVVLLV LLHRAKGGGL STLFGGGVQS SLSGSTVVEK NLDRLTLFVT
GIWLVSIIGV ALLIKYR