ID   SECY2_STAHJ             Reviewed;         399 AA.
AC   Q4L9N9;
DT   25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 117.
DE   RecName: Full=Accessory Sec system protein translocase subunit SecY2 {ECO:0000255|HAMAP-Rule:MF_01466};
GN   Name=secY2 {ECO:0000255|HAMAP-Rule:MF_01466}; OrderedLocusNames=SH0327;
OS   Staphylococcus haemolyticus (strain JCSC1435).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=279808;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC1435;
RX   PubMed=16237012; DOI=10.1128/jb.187.21.7292-7308.2005;
RA   Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA   Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA   Hiramatsu K.;
RT   "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT   extreme plasticity of its genome and the evolution of human-colonizing
RT   staphylococcal species.";
RL   J. Bacteriol. 187:7292-7308(2005).
CC   -!- FUNCTION: Part of the accessory SecA2/SecY2 system specifically
CC       required for export of possible cell wall proteins. The central subunit
CC       of a protein translocation channel. {ECO:0000255|HAMAP-Rule:MF_01466}.
CC   -!- SUBUNIT: Component of the accessory SecA2/SecY2 protein translocase
CC       complex required to export cell wall proteins. May form heterotrimers
CC       with SecE and SecG subunits. {ECO:0000255|HAMAP-Rule:MF_01466}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01466};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01466}.
CC   -!- SIMILARITY: Belongs to the SecY/SEC61-alpha family. SecY2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01466}.
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DR   EMBL; AP006716; BAE03636.1; -; Genomic_DNA.
DR   RefSeq; WP_011274655.1; NC_007168.1.
DR   AlphaFoldDB; Q4L9N9; -.
DR   SMR; Q4L9N9; -.
DR   STRING; 279808.SH0327; -.
DR   EnsemblBacteria; BAE03636; BAE03636; SH0327.
DR   KEGG; sha:SH0327; -.
DR   eggNOG; COG0201; Bacteria.
DR   HOGENOM; CLU_030313_4_0_9; -.
DR   OMA; LAMNITE; -.
DR   OrthoDB; 1567535at2; -.
DR   Proteomes; UP000000543; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.3370.10; -; 1.
DR   HAMAP; MF_01466; SecY2; 1.
DR   InterPro; IPR002208; SecY/SEC61-alpha.
DR   InterPro; IPR014269; SecY2.
DR   InterPro; IPR023201; SecY_dom_sf.
DR   PANTHER; PTHR10906; PTHR10906; 1.
DR   Pfam; PF00344; SecY; 1.
DR   PIRSF; PIRSF004557; SecY; 1.
DR   SUPFAM; SSF103491; SSF103491; 1.
DR   TIGRFAMs; TIGR02920; acc_sec_Y2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Protein transport; Translocation; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..399
FT                   /note="Accessory Sec system protein translocase subunit
FT                   SecY2"
FT                   /id="PRO_0000414871"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        128..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        184..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        238..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        272..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        335..355
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        362..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
SQ   SEQUENCE   399 AA;  45864 MW;  198762A95683406F CRC64;
     MIKKHEYKIL YKRILFTCFI LIVYIFGSNI SIVGSEGIYD NKDTFFKLAV SNVGGDLHTL
     NVFSLGLGPW LTSLVIIMLL NYRNLDQATK QTRSEKHYKE RIITIVFAIF QSYFVISTYI
     HNNFIKDSNI ILLMLILVAG TMLLVWLADQ NITYGICGPM PIVLTSLIKS LFNNQHFFKL
     SVSVLLLILV IVTLVIALLI LLFIELSEYR LNYKDIMNNS TNKTPTYLAW KLNPAGSISI
     MISLSVYVLL NNMINLIATL LGSNANFEFL SFANPIGIMF YIVLQIVLSY LLSRFLINTK
     KKADEFLKNG NYFDPIRPGR ETERYLNSKA RRVCWTGAIL VALILAVPLY STLLVPNLST
     EIYFSMQLII LVYISINIGE TIRTYLYFDR YKQILNKYW