ID   SECY2_STAPE             Reviewed;         407 AA.
AC   F0P5S5;
DT   25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT   03-MAY-2011, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Accessory Sec system protein translocase subunit SecY2 {ECO:0000255|HAMAP-Rule:MF_01466};
GN   Name=secY2 {ECO:0000255|HAMAP-Rule:MF_01466}; OrderedLocusNames=SPSE_0165;
OS   Staphylococcus pseudintermedius (strain ED99).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus; Staphylococcus intermedius group.
OX   NCBI_TaxID=984892;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ED99;
RX   PubMed=21398539; DOI=10.1128/jb.00137-11;
RA   Zakour N.L., Bannoehr J., van den Broek A.H., Thoday K.L., Fitzgerald J.R.;
RT   "Complete genome sequence of the canine pathogen Staphylococcus
RT   pseudintermedius.";
RL   J. Bacteriol. 193:2363-2364(2011).
CC   -!- FUNCTION: Part of the accessory SecA2/SecY2 system specifically
CC       required for export of possible cell wall proteins. The central subunit
CC       of a protein translocation channel. {ECO:0000255|HAMAP-Rule:MF_01466}.
CC   -!- SUBUNIT: Component of the accessory SecA2/SecY2 protein translocase
CC       complex required to export cell wall proteins. May form heterotrimers
CC       with SecE and SecG subunits. {ECO:0000255|HAMAP-Rule:MF_01466}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01466};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01466}.
CC   -!- SIMILARITY: Belongs to the SecY/SEC61-alpha family. SecY2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01466}.
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DR   EMBL; CP002478; ADX75512.1; -; Genomic_DNA.
DR   AlphaFoldDB; F0P5S5; -.
DR   SMR; F0P5S5; -.
DR   KEGG; sdt:SPSE_0165; -.
DR   PATRIC; fig|984892.3.peg.156; -.
DR   HOGENOM; CLU_030313_4_0_9; -.
DR   OMA; LAMNITE; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.3370.10; -; 1.
DR   HAMAP; MF_01466; SecY2; 1.
DR   InterPro; IPR002208; SecY/SEC61-alpha.
DR   InterPro; IPR014269; SecY2.
DR   InterPro; IPR023201; SecY_dom_sf.
DR   PANTHER; PTHR10906; PTHR10906; 1.
DR   Pfam; PF00344; SecY; 1.
DR   PIRSF; PIRSF004557; SecY; 1.
DR   SUPFAM; SSF103491; SSF103491; 1.
DR   TIGRFAMs; TIGR02920; acc_sec_Y2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Protein transport; Translocation; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..407
FT                   /note="Accessory Sec system protein translocase subunit
FT                   SecY2"
FT                   /id="PRO_0000414872"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        108..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        169..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        191..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        245..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        280..300
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        343..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        366..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
SQ   SEQUENCE   407 AA;  46804 MW;  9AF9CE755D8511C8 CRC64;
     MKNNRITKII NQYEYKIFYK RIAFTILILL IYILGSKITI VDENAMRQHD SAFYKLAVSN
     MGGDIHQLNV FSLGLGPWLT AMIIISLITY KNMEKAMHQT RAEKHYKEKF LTLGLSIIQG
     YFVINQFVRH TDAKRFTELL LLLILVTGAM LMMWLADQNM RYGIAGPMPI VLLSVIKSMF
     TQSLPIVSIE ILMLVVMVIL IIVALFILLL TELIEYRIHY RDIIEMPTPG QPTYLAWKIN
     PGGSISIMIS LSVFLLLTST INLIFNMVTG KTPHLQWLSF GHYMGVTIYL ILQTVLGYLL
     SRLIVNTKQN TKDFLKNGNY FIGIRPGADT GNYLNHLAKR LCWFGTTIVT AIIGVPLYIS
     LLVPDLSEYI YFAVQLMIMV YLAMNITETM RTYLYFDKYG AFLNQYW