ID   SECY2_STRE8             Reviewed;         408 AA.
AC   F8LR08;
DT   25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT   21-SEP-2011, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=Accessory Sec system protein translocase subunit SecY2 {ECO:0000255|HAMAP-Rule:MF_01466};
GN   Name=secY2 {ECO:0000255|HAMAP-Rule:MF_01466};
GN   OrderedLocusNames=SALIVA_1468;
OS   Streptococcus salivarius (strain JIM8777).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=347253;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JIM8777;
RX   PubMed=21742871; DOI=10.1128/jb.05390-11;
RA   Guedon E., Delorme C., Pons N., Cruaud C., Loux V., Couloux A., Gautier C.,
RA   Sanchez N., Layec S., Galleron N., Almeida M., van de Guchte M.,
RA   Kennedy S.P., Ehrlich S.D., Gibrat J.F., Wincker P., Renault P.;
RT   "Complete genome sequence of the commensal Streptococcus salivarius strain
RT   JIM8777.";
RL   J. Bacteriol. 193:5024-5025(2011).
CC   -!- FUNCTION: Part of the accessory SecA2/SecY2 system specifically
CC       required for export of possible cell wall proteins. The central subunit
CC       of a protein translocation channel. {ECO:0000255|HAMAP-Rule:MF_01466}.
CC   -!- SUBUNIT: Component of the accessory SecA2/SecY2 protein translocase
CC       complex required to export cell wall proteins. May form heterotrimers
CC       with SecE and SecG subunits. {ECO:0000255|HAMAP-Rule:MF_01466}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01466};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01466}.
CC   -!- SIMILARITY: Belongs to the SecY/SEC61-alpha family. SecY2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01466}.
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DR   EMBL; FR873482; CCB95778.1; -; Genomic_DNA.
DR   RefSeq; WP_014634786.1; NC_017595.1.
DR   AlphaFoldDB; F8LR08; -.
DR   KEGG; stj:SALIVA_1468; -.
DR   PATRIC; fig|347253.5.peg.1354; -.
DR   HOGENOM; CLU_030313_4_0_9; -.
DR   OMA; YSYLEIM; -.
DR   BioCyc; SSAL347253:SALIVA_RS07190-MON; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.3370.10; -; 1.
DR   HAMAP; MF_01466; SecY2; 1.
DR   InterPro; IPR002208; SecY/SEC61-alpha.
DR   InterPro; IPR014269; SecY2.
DR   InterPro; IPR023201; SecY_dom_sf.
DR   PANTHER; PTHR10906; PTHR10906; 1.
DR   Pfam; PF00344; SecY; 1.
DR   PIRSF; PIRSF004557; SecY; 1.
DR   SUPFAM; SSF103491; SSF103491; 1.
DR   TIGRFAMs; TIGR02920; acc_sec_Y2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Protein transport; Translocation; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..408
FT                   /note="Accessory Sec system protein translocase subunit
FT                   SecY2"
FT                   /id="PRO_0000414881"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        105..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        131..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        157..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        285..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        344..364
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        368..388
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
SQ   SEQUENCE   408 AA;  45722 MW;  0421EE167ECC30C1 CRC64;
     MKKISQSIIT KRVLWTLFFL FIYCLGNQLV LPFVDLKNAN IFGGAIGSLA FSSAMMGGNL
     RSMSLFSVGL SPWMSAMILW QMFSFSKKMG LKNLPIEIQD RRRMYLALGI AIVQSLAVSL
     NLPIVSGVNA SLAIFMNTIL LIAGTFFLVW LSDLNSLFGI GGSIVILMAS MMANLPYQIM
     DSIEKLGIGW NVLLPLILFS LVFLYVSGVV QRARYRISIN KINIHNRFKQ YSYLDIMLNP
     AGGMPFMYAM SLVSIPQYVF MLIQFIHPEN KWTSGAIKAL TVGQPLWLVV YLVMLFVLGL
     AFAFVNVSGE QISERMRKSG EYIYGVYPGQ ETSAYINHLV LRLGFIGALY MLFMAGAPML
     IILVNPDYLQ LSMIPGTFLI FSGMIYNVNE EMKALKLNTS YTPLFENV