ID   SECY2_STREH             Reviewed;         406 AA.
AC   F8LHW1;
DT   25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT   21-SEP-2011, sequence version 1.
DT   25-MAY-2022, entry version 43.
DE   RecName: Full=Accessory Sec system protein translocase subunit SecY2 {ECO:0000255|HAMAP-Rule:MF_01466};
GN   Name=secY2 {ECO:0000255|HAMAP-Rule:MF_01466};
GN   OrderedLocusNames=SALIVB_0631;
OS   Streptococcus salivarius (strain CCHSS3).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1048332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCHSS3;
RX   PubMed=21742894; DOI=10.1128/jb.05416-11;
RA   Delorme C., Guedon E., Pons N., Cruaud C., Couloux A., Loux V.,
RA   Chiapello H., Poyart C., Gautier C., Sanchez N., Almeida M., Kennedy S.P.,
RA   Ehrlich S.D., Gibrat J.F., Wincker P., Renault P.;
RT   "Complete genome sequence of the clinical Streptococcus salivarius strain
RT   CCHSS3.";
RL   J. Bacteriol. 193:5041-5042(2011).
CC   -!- FUNCTION: Part of the accessory SecA2/SecY2 system specifically
CC       required for export of possible cell wall proteins. The central subunit
CC       of a protein translocation channel. {ECO:0000255|HAMAP-Rule:MF_01466}.
CC   -!- SUBUNIT: Component of the accessory SecA2/SecY2 protein translocase
CC       complex required to export cell wall proteins. May form heterotrimers
CC       with SecE and SecG subunits. {ECO:0000255|HAMAP-Rule:MF_01466}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01466};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01466}.
CC   -!- SIMILARITY: Belongs to the SecY/SEC61-alpha family. SecY2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01466}.
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DR   EMBL; FR873481; CCB92931.1; -; Genomic_DNA.
DR   RefSeq; WP_013990275.1; NC_015760.1.
DR   AlphaFoldDB; F8LHW1; -.
DR   SMR; F8LHW1; -.
DR   EnsemblBacteria; CCB92931; CCB92931; SALIVB_0631.
DR   KEGG; ssr:SALIVB_0631; -.
DR   HOGENOM; CLU_030313_4_0_9; -.
DR   OMA; YSYLEIM; -.
DR   OrthoDB; 1567535at2; -.
DR   Proteomes; UP000000508; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.3370.10; -; 1.
DR   HAMAP; MF_01466; SecY2; 1.
DR   InterPro; IPR002208; SecY/SEC61-alpha.
DR   InterPro; IPR014269; SecY2.
DR   InterPro; IPR023201; SecY_dom_sf.
DR   PANTHER; PTHR10906; PTHR10906; 1.
DR   Pfam; PF00344; SecY; 1.
DR   PIRSF; PIRSF004557; SecY; 1.
DR   SUPFAM; SSF103491; SSF103491; 1.
DR   TIGRFAMs; TIGR02920; acc_sec_Y2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Protein transport; Translocation; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..406
FT                   /note="Accessory Sec system protein translocase subunit
FT                   SecY2"
FT                   /id="PRO_0000414880"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        108..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        131..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        156..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        190..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        285..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        344..364
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
FT   TRANSMEM        368..388
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01466"
SQ   SEQUENCE   406 AA;  45458 MW;  5DADB79AB119ADD6 CRC64;
     MKKILQSIVF KRLSWTVLFL FIYVLGSHLV LPFIDLKHPK LLGGLSNSIA FTSAMMGGNL
     SSFSLFSVGL SPWMSAMILW QMFSFSKKSG LSKLPIEIQD RRKMYLTFAI ALIQSLAVSL
     SLPIEVGIPK GLAILTNTIL LIAGTFFLVW LSDLNSFFGI GGSIVILMAS MVANLPRQIG
     ESITRLHIGL PIILSLIIMG LLFLYIAVIV QRARYRIPIN KVNIHNRFSQ YSYLDVMLTP
     AGGMPFMYAI SLVSIPQYLL ILIQILFPKN SWTNTWIEAL TVGHPIWLVL YQVVLFVLGI
     AFAFVNVSGE QIAERMRKSG EYIYNVYPGP DTSRYINKVV MKFAVIGAIY TVIMAGGPMM
     IVLINPQYLQ LSMIPGMFLI YSGMVYNVRE EIAAMTLNES YKGLFD