ID   SECY_CYAM1              Reviewed;         340 AA.
AC   Q85FU6;
DT   14-DEC-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Protein translocase subunit SecY {ECO:0000255|HAMAP-Rule:MF_01465};
GN   Name=secY {ECO:0000255|HAMAP-Rule:MF_01465};
OS   Cyanidioschyzon merolae (strain NIES-3377 / 10D) (Unicellular red alga).
OG   Plastid; Chloroplast.
OC   Eukaryota; Rhodophyta; Bangiophyceae; Cyanidiales; Cyanidiaceae;
OC   Cyanidioschyzon.
OX   NCBI_TaxID=280699;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIES-3377 / 10D;
RX   PubMed=12755171; DOI=10.1093/dnares/10.2.67;
RA   Ohta N., Matsuzaki M., Misumi O., Miyagishima S.-Y., Nozaki H., Tanaka K.,
RA   Shin-i T., Kohara Y., Kuroiwa T.;
RT   "Complete sequence and analysis of the plastid genome of the unicellular
RT   red alga Cyanidioschyzon merolae.";
RL   DNA Res. 10:67-77(2003).
CC   -!- FUNCTION: The central subunit of the protein translocation channel
CC       SecYE. Consists of two halves. These two domains form a lateral gate at
CC       the front which open onto the bilayer between TMs 2 and 7, and are
CC       clamped together by SecE at the back. The channel is closed by both a
CC       pore ring composed of hydrophobic SecY resides and a short helix (helix
CC       2A) on the extracellular side of the membrane which forms a plug (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the plastid Sec protein translocase complex,
CC       which is composed of at least SecY and SecE. {ECO:0000255|HAMAP-
CC       Rule:MF_01465}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC       {ECO:0000255|HAMAP-Rule:MF_01465}; Multi-pass membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_01465}.
CC   -!- SIMILARITY: Belongs to the SecY/SEC61-alpha family. {ECO:0000255|HAMAP-
CC       Rule:MF_01465}.
CC   -!- CAUTION: Bioinformatics prediction programs detect only 8 instead of 10
CC       transmembrane regions. {ECO:0000305}.
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DR   EMBL; AB002583; BAC76248.1; -; Genomic_DNA.
DR   RefSeq; NP_849086.1; NC_004799.1.
DR   AlphaFoldDB; Q85FU6; -.
DR   SMR; Q85FU6; -.
DR   STRING; 45157.CMV181CT; -.
DR   EnsemblPlants; CMV181CT; CMV181CT; CMV181C.
DR   GeneID; 845021; -.
DR   Gramene; CMV181CT; CMV181CT; CMV181C.
DR   KEGG; cme:CymeCp154; -.
DR   eggNOG; ENOG502QSNV; Eukaryota.
DR   HOGENOM; CLU_030313_0_0_1; -.
DR   Proteomes; UP000007014; Chloroplast.
DR   GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.3370.10; -; 1.
DR   HAMAP; MF_01465; SecY; 1.
DR   InterPro; IPR026593; SecY.
DR   InterPro; IPR002208; SecY/SEC61-alpha.
DR   InterPro; IPR030659; SecY_CS.
DR   InterPro; IPR023201; SecY_dom_sf.
DR   PANTHER; PTHR10906; PTHR10906; 2.
DR   Pfam; PF00344; SecY; 1.
DR   SUPFAM; SSF103491; SSF103491; 1.
DR   PROSITE; PS00756; SECY_2; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Membrane; Plastid; Protein transport; Reference proteome;
KW   Thylakoid; Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..340
FT                   /note="Protein translocase subunit SecY"
FT                   /id="PRO_0000414216"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        225..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        282..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        304..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
SQ   SEQUENCE   340 AA;  38022 MW;  5BD6AB333913FB0B CRC64;
     MQDNWPTRLA ITCLLVAIER LGMYIPVGLI SNPQANWLNG GGWFVLGIIP TINASIVMQI
     LISIVPALTR LQKEEGEMGQ KQIQKYTRYL TFFLAGIQAF TLSQQWCTWL LIVSGAMLVM
     WLAEQMTHKG IGNGTSIFVC SNIAANFLHH PIEAPWSLAM VVLIFTMLGM IALQEAVRAI
     PILSAKQLIQ SIAQVYLLPM RLNQGGVMPI IFASSTLALL HTWSIWWLYV ACIIFFSHFY
     NLVIANPKEL SENLNKMAVV IPSIRPGAET QQYLNRTLNR MSWIGGIALS LIALLPWLFS
     SLKIFSGFGA TSLLIVIGVS IDTMRQIRTY FIANAYEKMI