ID   SECY_HETA2              Reviewed;         454 AA.
AC   B2XTD8;
DT   14-DEC-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   03-AUG-2022, entry version 44.
DE   RecName: Full=Protein translocase subunit SecY {ECO:0000255|HAMAP-Rule:MF_01465};
GN   Name=secY {ECO:0000255|HAMAP-Rule:MF_01465};
GN   OrderedLocusNames=Heak293_Cp129;
OS   Heterosigma akashiwo (strain NIES-293 / 8280G21-1).
OG   Plastid; Chloroplast.
OC   Eukaryota; Sar; Stramenopiles; Ochrophyta; Raphidophyceae; Chattonellales;
OC   Chattonellaceae; Heterosigma.
OX   NCBI_TaxID=536047;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=18462506; DOI=10.1186/1471-2164-9-211;
RA   Cattolico R.A., Jacobs M.A., Zhou Y., Chang J., Duplessis M., Lybrand T.,
RA   McKay J., Ong H.C., Sims E., Rocap G.;
RT   "Chloroplast genome sequencing analysis of Heterosigma akashiwo CCMP452
RT   (West Atlantic) and NIES293 (West Pacific) strains.";
RL   BMC Genomics 9:211-211(2008).
CC   -!- FUNCTION: The central subunit of the protein translocation channel
CC       SecYE. Consists of two halves formed by TMs 1-5 and 6-10. These two
CC       domains form a lateral gate at the front which open onto the bilayer
CC       between TMs 2 and 7, and are clamped together by SecE at the back. The
CC       channel is closed by both a pore ring composed of hydrophobic SecY
CC       resides and a short helix (helix 2A) on the extracellular side of the
CC       membrane which forms a plug. {ECO:0000255|HAMAP-Rule:MF_01465}.
CC   -!- SUBUNIT: Component of the plastid Sec protein translocase complex,
CC       which is composed of at least SecY and SecE. {ECO:0000255|HAMAP-
CC       Rule:MF_01465}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC       {ECO:0000255|HAMAP-Rule:MF_01465}; Multi-pass membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_01465}.
CC   -!- SIMILARITY: Belongs to the SecY/SEC61-alpha family. {ECO:0000255|HAMAP-
CC       Rule:MF_01465}.
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DR   EMBL; EU168190; ABV66036.1; -; Genomic_DNA.
DR   RefSeq; YP_001936430.1; NC_010772.1.
DR   AlphaFoldDB; B2XTD8; -.
DR   SMR; B2XTD8; -.
DR   GeneID; 6335582; -.
DR   GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.3370.10; -; 1.
DR   HAMAP; MF_01465; SecY; 1.
DR   InterPro; IPR026593; SecY.
DR   InterPro; IPR002208; SecY/SEC61-alpha.
DR   InterPro; IPR023201; SecY_dom_sf.
DR   PANTHER; PTHR10906; PTHR10906; 1.
DR   Pfam; PF00344; SecY; 1.
DR   PIRSF; PIRSF004557; SecY; 1.
DR   SUPFAM; SSF103491; SSF103491; 1.
DR   TIGRFAMs; TIGR00967; 3a0501s007; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Membrane; Plastid; Protein transport; Thylakoid;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..454
FT                   /note="Protein translocase subunit SecY"
FT                   /id="PRO_0000414217"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        168..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        201..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        289..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        334..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        390..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        414..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
SQ   SEQUENCE   454 AA;  50963 MW;  C14BDA0092BCDD56 CRC64;
     MTLEKNKDSF TNIIDLSLIN KEQKVTFTPT KEIYTELLKK RLLTIALLVF IIKIGMAIPL
     PYIDQTKLLN NATSMFDLSG PGLAAVSARA SQKIGLFTLG ITPSINASII LQLAFVINPN
     LKKLQREEGE SGRRKLIKYT RYLTLLLAIT QSVFLIFSLR AFIFEWSILK LFELSCVLSS
     GAMIILWISE CITKTGITNG SSFLIFLNIV SVLPEQIGMS FKNLDIFSFE GLIVILTFSI
     TVWAAIFLQQ TLYIIPLKNP KLGQNELTKK LVEDSLYLPF RLNQAGVMPV VFASYLIPIL
     KTGGIYILLK INSFNLFPFL IKFPEVVNQS LESIVEAGLI CLFALFYSGL IIDPKDVADE
     LQKSGFFIFA IRPGEKTRNY LEKIFKELSL IGALILAFNV VLLNLVGFVF NLSIFKGFSI
     GSQIILLGVV TEILQKVQAL VLNDVYKRIR DRNK