ID   SECY_MAIZE              Reviewed;         553 AA.
AC   O63066; O47005;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Preprotein translocase subunit SECY, chloroplastic;
DE   AltName: Full=CpSecY;
DE   Flags: Precursor;
GN   Name=SECY; Synonyms=CSY1;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RC   STRAIN=cv. B73;
RX   PubMed=9548717; DOI=10.1083/jcb.141.2.385;
RA   Roy L.M., Barkan A.;
RT   "A SecY homologue is required for the elaboration of the chloroplast
RT   thylakoid membrane and for normal chloroplast gene expression.";
RL   J. Cell Biol. 141:385-395(1998).
CC   -!- FUNCTION: The central subunit of the protein translocation channel
CC       SecYE. Consists of two halves formed by TMs 1-5 and 6-10. These two
CC       domains form a lateral gate at the front which open onto the bilayer
CC       between TMs 2 and 7, and are clamped together by SecE at the back. The
CC       channel is closed by both a pore ring composed of hydrophobic SecY
CC       resides and a short helix (helix 2A) on the extracellular side of the
CC       membrane which forms a plug (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the plastid Sec protein translocase complex,
CC       which is composed of at least SECY and SECE. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC       {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SecY/SEC61-alpha family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB96657.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AF039304; AAC05019.1; -; mRNA.
DR   EMBL; AF039305; AAB96657.1; ALT_SEQ; Genomic_DNA.
DR   PIR; T01416; T01416.
DR   PIR; T01432; T01432.
DR   AlphaFoldDB; O63066; -.
DR   SMR; O63066; -.
DR   STRING; 4577.GRMZM5G809546_P01; -.
DR   PaxDb; O63066; -.
DR   eggNOG; ENOG502QSNV; Eukaryota.
DR   Proteomes; UP000007305; Unplaced.
DR   ExpressionAtlas; O63066; baseline and differential.
DR   GO; GO:0009535; C:chloroplast thylakoid membrane; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0005048; F:signal sequence binding; IBA:GO_Central.
DR   GO; GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; IBA:GO_Central.
DR   Gene3D; 1.10.3370.10; -; 1.
DR   HAMAP; MF_01465; SecY; 1.
DR   InterPro; IPR026593; SecY.
DR   InterPro; IPR002208; SecY/SEC61-alpha.
DR   InterPro; IPR030659; SecY_CS.
DR   InterPro; IPR023201; SecY_dom_sf.
DR   PANTHER; PTHR10906; PTHR10906; 1.
DR   Pfam; PF00344; SecY; 1.
DR   SUPFAM; SSF103491; SSF103491; 1.
DR   TIGRFAMs; TIGR00967; 3a0501s007; 1.
DR   PROSITE; PS00755; SECY_1; 1.
DR   PROSITE; PS00756; SECY_2; 1.
PE   2: Evidence at transcript level;
KW   Chloroplast; Membrane; Plastid; Protein transport; Reference proteome;
KW   Thylakoid; Transit peptide; Translocation; Transmembrane;
KW   Transmembrane helix; Transport.
FT   TRANSIT         1..?
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..553
FT                   /note="Preprotein translocase subunit SECY, chloroplastic"
FT                   /id="PRO_0000031996"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        243..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        270..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        297..317
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        330..350
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        384..404
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        417..437
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        482..502
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        505..525
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   553 AA;  59354 MW;  641A3E5D3F340417 CRC64;
     MVTATTTPPQ CWRGLPALAR APPPLSSPLR PRAVAAAAPI YPLRRRIAIT TTRGRRGTLD
     CSPRCTLETA GPGFDPLGLY EEGSNSLSRS PLSTFFGIMA PVFGSSSGGG ASREKASGRG
     AAAAIEDSSI DIGDFFKGPL PGKFLKLLGF LALSRLGVYI PLGGVNREAF AGNLDQNSLL
     GTLDSFSGGG IGRLGICSLG IVPFINAQIV FQLLAQLYPK LQDLQRKEGE AGRKKVLQYT
     RYASVGFAIV QAIGQVLYLR PYVNDFSTEW VLTSVTLLTL GSVFTTFIGE RISDLKLGNG
     TSLLIFTSII SYLPASFGRT VAQAFQDGNY VGLLTIILSF LLLVLGIVYV QEAERKIPLN
     YASRYSSRTG ELQRSAYLPF KVNSSGVMPI IFSTSSLALP GTLARFSGLD FLKKAAIALN
     PGGALYLPTN VLLIAFFNYY YTFLQLDPDD LSEQLKRQGA SIPLVRPGKS TAAYIKTVLN
     RISVLGSAFL AVLAAGPSLV EQTSHLTAFR GFAGTSVLIL VGCATDTARK VQAEIISQKY
     KNIEFYDVNR FGQ