ID   SECY_PYRSA              Reviewed;         412 AA.
AC   P38397;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Protein translocase subunit SecY {ECO:0000255|HAMAP-Rule:MF_01465};
DE   Flags: Fragment;
GN   Name=secY {ECO:0000255|HAMAP-Rule:MF_01465};
OS   Pyrenomonas salina.
OG   Plastid; Chloroplast.
OC   Eukaryota; Cryptophyceae; Pyrenomonadales; Pyrenomonadaceae; Pyrenomonas.
OX   NCBI_TaxID=3034;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7820283; DOI=10.1006/mpev.1994.1021;
RA   Rensing S.A., Maier U.-G.;
RT   "The SecY protein family: comparative analysis and phylogenetic
RT   relationships.";
RL   Mol. Phylogenet. Evol. 3:187-191(1994).
CC   -!- FUNCTION: The central subunit of the protein translocation channel
CC       SecYE. Consists of two halves formed by TMs 1-5 and 6-10. These two
CC       domains form a lateral gate at the front which open onto the bilayer
CC       between TMs 2 and 7, and are clamped together by SecE at the back. The
CC       channel is closed by both a pore ring composed of hydrophobic SecY
CC       resides and a short helix (helix 2A) on the extracellular side of the
CC       membrane which forms a plug. {ECO:0000255|HAMAP-Rule:MF_01465}.
CC   -!- SUBUNIT: Component of the plastid Sec protein translocase complex,
CC       which is composed of at least SecY and SecE. {ECO:0000255|HAMAP-
CC       Rule:MF_01465}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC       {ECO:0000255|HAMAP-Rule:MF_01465}; Multi-pass membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_01465}.
CC   -!- SIMILARITY: Belongs to the SecY/SEC61-alpha family. {ECO:0000255|HAMAP-
CC       Rule:MF_01465}.
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DR   EMBL; X74773; CAA52783.1; -; Genomic_DNA.
DR   AlphaFoldDB; P38397; -.
DR   SMR; P38397; -.
DR   GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3370.10; -; 1.
DR   HAMAP; MF_01465; SecY; 1.
DR   InterPro; IPR026593; SecY.
DR   InterPro; IPR002208; SecY/SEC61-alpha.
DR   InterPro; IPR030659; SecY_CS.
DR   InterPro; IPR023201; SecY_dom_sf.
DR   PANTHER; PTHR10906; PTHR10906; 1.
DR   Pfam; PF00344; SecY; 1.
DR   PIRSF; PIRSF004557; SecY; 1.
DR   SUPFAM; SSF103491; SSF103491; 1.
DR   TIGRFAMs; TIGR00967; 3a0501s007; 1.
DR   PROSITE; PS00755; SECY_1; 1.
DR   PROSITE; PS00756; SECY_2; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Membrane; Plastid; Protein transport; Thylakoid;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..>412
FT                   /note="Protein translocase subunit SecY"
FT                   /id="PRO_0000131779"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        117..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        170..190
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        251..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        293..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        350..370
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   TRANSMEM        372..392
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01465"
FT   NON_TER         412
SQ   SEQUENCE   412 AA;  45869 MW;  79763DB2CBE6B90D CRC64;
     MESIRRNSRK EGIKERIFLT IGLLVLSRLG TFIPVPGVDH DAFYQSISTN PIVTFLNIFS
     GGGFASIGIF ALGIVPYINA SIVIQLATTS IPNLEKLQKE EGEAGRQKIS QITRYRALGW
     AAIQSLGVSF WVRPYVFNWD SQFVVQMTLA LTTGSMLIMW FSEQITEKGI GNGPSLLIFI
     NIIAGLPKLI QQKSNAISST NQTTELVVLA SISVYDSRIF IRDRRYYILQ TVGRHCKQTS
     YLPLRLNQGG VMPIIFASAI LVLPAYLGQV IQNQFVLKLV TLLSPNSSDK NLYLIFYFSL
     ILFFSYFYAS LIINPNDVSQ NLKKMESSIP GVRPGKATTD YLQKTLNRLT FLGALFLAFI
     AVVPSIIENI TSISTFKGLG ATSLLILVGV AIDTSRQIQT YLISRNYENI MK