ID   SEGA_BPT4               Reviewed;         221 AA.
AC   P32286;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   02-JUN-2021, entry version 82.
DE   RecName: Full=Endonuclease segA;
DE            EC=3.1.-.-;
DE   AltName: Full=Endodeoxyribonuclease segA;
GN   Name=segA;
OS   Enterobacteria phage T4 (Bacteriophage T4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
OX   NCBI_TaxID=10665;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1631169; DOI=10.1073/pnas.89.14.6658;
RA   Sharma M., Ellis R.L., Hinton D.M.;
RT   "Identification of a family of bacteriophage T4 genes encoding proteins
RT   similar to those present in group I introns of fungi and phage.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:6658-6662(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12626685; DOI=10.1128/mmbr.67.1.86-156.2003;
RA   Miller E.S., Kutter E., Mosig G., Arisaka F., Kunisawa T., Ruger W.;
RT   "Bacteriophage T4 genome.";
RL   Microbiol. Mol. Biol. Rev. 67:86-156(2003).
CC   -!- FUNCTION: Probably involved in the movement of the endonuclease-
CC       encoding DNA.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC   -!- SIMILARITY: To endonucleases of group I introns of fungi and phage.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M69268; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AF158101; AAD42654.1; -; Genomic_DNA.
DR   PIR; A46026; A46026.
DR   RefSeq; NP_049657.1; NC_000866.4.
DR   REBASE; 2955; F-TevI.
DR   GeneID; 1258777; -.
DR   KEGG; vg:1258777; -.
DR   Proteomes; UP000009087; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR   InterPro; IPR003611; NUMOD3.
DR   Pfam; PF01541; GIY-YIG; 1.
DR   Pfam; PF07460; NUMOD3; 2.
DR   SMART; SM00465; GIYc; 1.
DR   SMART; SM00496; IENR2; 2.
DR   SUPFAM; SSF82771; SSF82771; 1.
DR   PROSITE; PS50164; GIY_YIG; 1.
PE   4: Predicted;
KW   Endonuclease; Hydrolase; Magnesium; Nuclease; Reference proteome.
FT   CHAIN           1..221
FT                   /note="Endonuclease segA"
FT                   /id="PRO_0000164980"
FT   DOMAIN          8..91
FT                   /note="GIY-YIG"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00977"
FT   REGION          137..164
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   221 AA;  25339 MW;  B3313531873ACAAD CRC64;
     MKRHKEKKYN YTYVITNLVN NKIYYGTHST DDLNDGYMGS GTLLAQAKKK YGKKNFNLSI
     LGFYKDFKSA RDAERELVTI DVVNDPMTYN LKIGGEGGRR IGYRVSSETK EKISKAQKGK
     PKHLGFSDVC RKAQLGKKQS EETKAKRKEA LLNNPYGYNR NKPSHKRDPI MWDNIEKIKE
     IWENSGKSGA IKLKKLAIEA GFPNKSYARM LEVFRGTRTL L