ID   SEGE_BPT4               Reviewed;         205 AA.
AC   P18060; Q9T0T9;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   19-DEC-2001, sequence version 2.
DT   23-FEB-2022, entry version 95.
DE   RecName: Full=Putative endonuclease segE;
DE            EC=3.1.-.-;
DE   AltName: Full=Endodeoxyribonuclease segE;
GN   Name=segE; Synonyms=hoc.2;
OS   Enterobacteria phage T4 (Bacteriophage T4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
OX   NCBI_TaxID=10665;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2377482; DOI=10.1093/nar/18.14.4277;
RA   Kaliman A.V., Khasanova M.A., Kryukov V.M., Tanyashin V.I., Bayev A.A.;
RT   "The nucleotide sequence of the region of bacteriophage T4 inh(lip)-hoc
RT   genes.";
RL   Nucleic Acids Res. 18:4277-4277(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12626685; DOI=10.1128/mmbr.67.1.86-156.2003;
RA   Miller E.S., Kutter E., Mosig G., Arisaka F., Kunisawa T., Ruger W.;
RT   "Bacteriophage T4 genome.";
RL   Microbiol. Mol. Biol. Rev. 67:86-156(2003).
RN   [3]
RP   IDENTIFICATION, AND POSSIBLE FUNCTION.
RX   PubMed=1631169; DOI=10.1073/pnas.89.14.6658;
RA   Sharma M., Ellis R.L., Hinton D.M.;
RT   "Identification of a family of bacteriophage T4 genes encoding proteins
RT   similar to those present in group I introns of fungi and phage.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:6658-6662(1992).
CC   -!- FUNCTION: Probably involved in the movement of the endonuclease-
CC       encoding DNA.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC   -!- SIMILARITY: To endonucleases of group I introns of fungi and phage.
CC       {ECO:0000305}.
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DR   EMBL; X14869; CAA33013.1; -; Genomic_DNA.
DR   EMBL; AF158101; AAD42658.1; -; Genomic_DNA.
DR   PIR; JQ0565; S10497.
DR   RefSeq; NP_049795.1; NC_000866.4.
DR   SMR; P18060; -.
DR   REBASE; 3006; F-TevII.
DR   GeneID; 1258802; -.
DR   KEGG; vg:1258802; -.
DR   Proteomes; UP000009087; Genome.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.1440.10; -; 1.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR   InterPro; IPR045566; SegE_GIY-YIG.
DR   Pfam; PF19835; SegE_GIY-YIG; 1.
DR   SMART; SM00465; GIYc; 1.
DR   SUPFAM; SSF82771; SSF82771; 1.
DR   PROSITE; PS50164; GIY_YIG; 1.
PE   4: Predicted;
KW   Endonuclease; Hydrolase; Magnesium; Nuclease; Reference proteome.
FT   CHAIN           1..205
FT                   /note="Putative endonuclease segE"
FT                   /id="PRO_0000164984"
FT   DOMAIN          1..84
FT                   /note="GIY-YIG"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00977"
FT   CONFLICT        87
FT                   /note="G -> S (in Ref. 1; CAA33013)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        127
FT                   /note="T -> S (in Ref. 1; CAA33013)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        135
FT                   /note="G -> R (in Ref. 1; CAA33013)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   205 AA;  22895 MW;  614AAEFF992CC2B7 CRC64;
     MYHFVYETTN LINGKKYIGK HSTDDLNDGY LGSGKAIQQA IKKYGENNFS RTILKEFKTS
     EEAYMYEEEI ITPELIKSKN YYNMKPGGIG GIVMTTDVIA KMKESSAKRF ENSPGTVLGK
     TCYTNGTKNI FIKPGELVPE GFVKGMVHPN RKSRKGCKVK PTTTGTFWVN NGAINKLIQP
     DGIIPDGFIK GRLMKRDSKG KFSKA