SELK_DICDI
ID SELK_DICDI Reviewed; 115 AA.
AC Q55EX3;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 29-APR-2008, sequence version 2.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=Selenoprotein K homolog;
GN Name=selk; ORFNames=DDB_G0268720;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the selenoprotein K family. {ECO:0000305}.
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DR EMBL; AAFI02000004; EAL72949.2; -; Genomic_DNA.
DR RefSeq; XP_646897.2; XM_641805.2.
DR PaxDb; Q55EX3; -.
DR EnsemblProtists; EAL72949; EAL72949; DDB_G0268720.
DR GeneID; 8616582; -.
DR KEGG; ddi:DDB_G0268720; -.
DR dictyBase; DDB_G0268720; selk.
DR eggNOG; ENOG502RIJT; Eukaryota.
DR HOGENOM; CLU_2113551_0_0_1; -.
DR InParanoid; Q55EX3; -.
DR OMA; VFFTTMF; -.
DR PRO; PR:Q55EX3; -.
DR Proteomes; UP000002195; Chromosome 1.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0006816; P:calcium ion transport; IBA:GO_Central.
DR GO; GO:0032469; P:endoplasmic reticulum calcium ion homeostasis; IBA:GO_Central.
DR InterPro; IPR024491; Se_SelK/SelG.
DR PANTHER; PTHR16875; PTHR16875; 1.
DR Pfam; PF10961; SelK_SelG; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Selenocysteine; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..115
FT /note="Selenoprotein K homolog"
FT /id="PRO_0000328438"
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 47..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_STD 112
FT /note="Selenocysteine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 115 AA; 12036 MW; DAEB02867764FB83 CRC64;
MPPKPTYVSG GSVTQTGRSK WRLSYIPEFI WGILNQITFF FSTLIGGTVE PRRRPNNQGG
GRRLAGFDGN GNVTGGSGVG GSGPSKGPDN GSNNRRGDMK NILACNSASG SUGPK
